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1、·對(duì)比FDA和CFDA批準(zhǔn)的抗癌藥物列表?！ぐl(fā)現(xiàn)事實(shí)。下面的都是FDA批準(zhǔn)的靶點(diǎn)藥，而有中文名稱的是CFDA允許在國(guó)內(nèi)銷售的。可以說(shuō)，國(guó)內(nèi)病人基本享受不到自從05年以來(lái)的絕大多數(shù)抗癌研究成果。為父親大人學(xué)習(xí)相關(guān)知識(shí)。AgentTarget(s)FDA-approvedindication(s)CFDAapprovedAdo-trastuzumabemtansine(Kadcyla)HER2(ERBB2/neu)Breastcancer(HER2+) Afatinib(Gilotrif)EGFR(HER1/ERBB1),HER2(E
2、RBB2/neu)Non-smallcelllungcancer(withEGFRexon19deletionsorexon21substitution(L858R)mutations) Aldesleukin(Proleukin) Renalcellcarcinoma Melanoma Alemtuzumab(Campath)CD52B-cellchroniclymphocyticleukemia Axitinib(Inlyta)KIT,PDGFRβ,VEGFR1/2/3Renalcellcarcinoma Belimuma
3、b(Benlysta)BAFFLupuserythematosus Belinostat(Beleodaq)HDACPeripheralT-celllymphoma Bevacizumab(Avastin)VEGFligandCervicalcancer貝伐珠單抗注射液 Colorectalcancer Fallopiantubecancer Glioblastoma Non-smallcelllungcancer Ovariancancer Peritonealcancer Renalcellcarci
4、noma Bortezomib(Velcade)ProteasomeMultiplemyeloma注射用硼替佐米?[1]?
5、?2014-12-3011:28jastee Mantlecelllymphoma Bosutinib(Bosulif)ABLChronicmyelogenousleukemia(Philadelphiachromosomepositive) Brentuximabvedotin(Adcetris)CD30Hodgkinlymphoma Anaplasticlargecelllymphoma Caboz
6、antinib(Cometriq)FLT3,KIT,MET,RET,VEGFR2Medullarythyroidcancer Canakinumab(Ilaris)IL-1βJuvenileidiopathicarthritis Cryopyrin-associatedperiodicsyndromes Carfilzomib(Kyprolis)ProteasomeMultiplemyeloma Ceritinib(Zykadia)ALKNon-smallcelllungcancer(withALKfusion) Cetuxi
7、mab(Erbitux)EGFR(HER1/ERBB1)Colorectalcancer(KRASwildtype)西妥昔單抗注射液 Squamouscellcanceroftheheadandneck Crizotinib(Xalkori)ALK,METNon-smallcelllungcancer(withALKfusion)克唑替尼膠囊Dabrafenib(Tafinlar)BRAFMelanoma(withBRAFV600mutation) Dasatinib(Sprycel)ABLChronicmyelogenousl
8、eukemia(Philadelphiachromosomepositive)達(dá)沙替尼片 Acutelymphoblasticleukemia(Philadelphiachromosomepositive) Denosumab(Xgeva)RANKLGiantcelltumorofthebone Erlotinib(Tarceva)EGFR(HER1/ERBB1)Non-smallcelllungcancer鹽酸厄洛替尼片 Pancreaticcancer Everolimus(Afinitor)mTORPancreaticn
9、euroendocrinetumor依維莫司片 Renalcellcarcinoma Nonresectablesubependymalgiantcellastrocytomaassociatedwithtuberoussclerosis
