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《大鼠急性缺血性腦損傷后星形膠質(zhì)細(xì)胞的活動與藥物對其影響的分析》由會員上傳分享，免費在線閱讀，更多相關(guān)內(nèi)容在行業(yè)資料-天天文庫。
1、AbstractsignificancetoaffectthenumberofGFAP—positivecellsinhippocampalCAIarea，P=0．000，P=O．000，P=O．028，theinteractionbetweentheoperationlevelandusemannitolornothadstatisticalsignificance，P=O．000，Thestatisticalresultsindicatedthattherewasasynergisticeffectbetweenthetwo．Allthediff
2、erencesofGFAP—positivecellsinhippocampalCA1areabetweencontrolgroupandshamoperationgroup，thecontrolgroupandmodelgroupandshamoperationgroupandmodelgroupbytheTukeyHSDtesthadstatisticalsignificance，allthreeP=0．000．Conclusion：Thisstudyfindsoutthat，tosomeextent，itstillCannotbethought
3、thatinfluenceofdifferentdosesofmannitoltotheactivitiyofASaroundtheischemiclesionandinhippocampalCA1areaonischemia—reperfusionmodelratsaredifferent．RatsmNSSscorevaluesandtheperipheralischemiclesionandhippocampalCA1areawerenegativelycorrelatedwiththenumberofAS，thatis：mNSSscoreval
4、uesreduceifthenumberofASincrease，neurologicbehavioralperformancegetsbetter．ThisstudydemonstratedthatASreactivehyperplasiaoccursignificantlyaroundtheischemiclesionandinhippocampalCAlareaafteracuteischemicbraininjuryinrats．24hor72hafterusingmannitolwillbothsignificantlyincreaseth
5、eactivityofASreactionintheperipheralischemiclesionandhippocampalCA1areainischemia-reperfusionmodelrats．Itcanbeinferredthatusingmannitolafteracuteischemicbraininjury,mayprotectischemicbraintissueandsurroundingtissuebyincreasingtheASreactionactivityinperipheralischemiclesionandhi
6、ppocampalCAlarea．Keywords：astrocyte；GFAP；ischemia-reperfusionmodel；mannitolV英文縮略訪J表英文縮略詞表英文縮寫英文全稱MCAOmiddlecerebralarteryocclusionMCAmiddlecerebralarteryGFAPglialfibrillaryacidicproteinmNSSmodifiedneurologicalseverityscoreTTC2，3，5一Triphenyl一2h-TetrazoliumChlorideCNScentralnervo
7、ussystemBBBBlood．BrainBarrierSABCstreptavidin·-biotin·-peroxidasecomplexPBSDABCCAICAECAPPAPhosphateBufferedSalineDiaminobenzidinecommoncarotidarteryinternalcarotidarteryexternalcarotidarterypterygopalatinearteryVII中文全稱大腦中動脈阻塞大腦中動脈膠質(zhì)纖維酸性蛋白改良的神經(jīng)功能缺損評分2，3，5．氯化三苯基四氮嘩中樞神經(jīng)系統(tǒng)血腦屏障鏈酶親和素
8、．生物素．過氧化物酶復(fù)合物磷酸鹽緩沖液二氨基聯(lián)苯胺頸總動脈頸內(nèi)動脈頸外動脈翼腭動脈第l章前高第1章前言缺血性
