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1、SystemsBiologyPhilosophicalFoundationsThispageintentionallyleftblankSystemsBiologyPhilosophicalFoundationsEditedbyFredC.BoogerdandFrankJ.BruggemanDepartmentofMolecularCellPhysiologyFacultyofEarthandLifeSciencesVrijeUniversiteit,Amsterdam,TheNetherlandsJan-HendrikS.HofmeyrDepartmentofBiochemistry,
2、FacultyofScienceUniversityofStellenbosch,Stellenbosch,SouthAfricaHansV.WesterhoffDepartmentofMolecularCellPhysiologyFacultyofEarthandLifeSciencesVrijeUniversiteit,Amsterdam,TheNetherlandsandManchesterCentreforIntegrativeSystemsBiologyTheUniversityofManchester,Manchester,UnitedKingdomAmsterdam?Bos
3、ton?Heidelberg?London?NewYork?OxfordParis?SanDiego?SanFrancisco?Singapore?Sydney?TokyoElsevierRadarweg29,POBox211,1000AEAmsterdam,TheNetherlandsTheBoulevard,LangfordLane,Kidlington,OxfordOX51GB,UKFirstedition2007Copyright?2007ElsevierB.V.AllrightsreservedNopartofthispublicationmaybereproduced,sto
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6、iability,negligenceorotherwise,orfromanyuseoroperationofanymethods,products,instructionsorideascontainedinthematerialherein.Becauseofrapidadvancesinthemedicalsciences,inparticular,independentverificationofdiagnosesanddrugdosagesshouldbemadeLibraryofCongressCataloging-in-PublicationDataAcatalogrec
7、ordforthisbookisavailablefromtheLibraryofCongressBritishLibraryCataloguinginPublicationDataAcataloguerecordforthisbookisavailablefromtheBritishLibraryISBN-13:978-0-444-52085-2ISBN-10:0-444-52085-6ForinformationonallEls
