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1、發(fā)生于胃的胃腸間質(zhì)瘤外科治療臨床醫(yī)藥實踐雜志2006年9月第15卷第9期bentassayforconnectivetissuegrowthfactor(CTGF)anditsdetectionintheseraofbiliaryatresia[JJ.BiochemBiophysResCommum,1998,251(3):748.[4]SAEGUSA,ISAJIS,KAwARADAY.ChangesinserumbyaalaronicacidlevelsandexpressionofCD44MRNAinhepaticsinusoidalendothelialcellafter?
2、■661?majarhepatectomyincirrhoticrats[J].WorldJSurg,2002,26(6):694—696.
3、5]BIOMlE,GOIDSCHMEDINGR,LCASKA.Generegulationofconucotivetissuegrowthfactornewtargetsforantifibrotictheraphy?[J].MATRIXBi一01,2002.21(6):4.收稿日期:2006—07—03作者簡介:李蓉(1970一)，女，內(nèi)蒙古人，碩士學位，主治醫(yī)生,主要從事消化內(nèi)科工作.文章編號;1671—8631(2006)09?06
4、61—03發(fā)生于胃的胃腸間質(zhì)瘤外科治療韓學東(南京醫(yī)科大學附屬淮安第一醫(yī)院淮安市第一人民醫(yī)院，江蘇淮安223300)摘要目的:探討發(fā)生于胃的胃腸問質(zhì)瘤(GIST)外科治療的方法?方法:對1995年8月?2005年8月收治的經(jīng)手術(shù)病理證實的19例胃GIST進行回顧性研究.結(jié)果:19例患者中,腫瘤位于賁門胃底區(qū)7例，胃體9例，胃竇3例.腫瘤最小2cm,最大25cm,中位大小6cm.胃周淋巴結(jié)轉(zhuǎn)移1例.手術(shù)行胃楔形切除11例，近端胃大部切除5例，遠端胃大部切除3例，其中聯(lián)合臟器切除3例.查免疫組織化學CDII7陽性16例,CD34陽性17例.術(shù)后隨診5例復發(fā)轉(zhuǎn)移.結(jié)論:胃GIST治療
5、以手術(shù)為主,術(shù)中應(yīng)根據(jù)腫瘤大小，部位，有無外侵及淋巴結(jié)轉(zhuǎn)移決定手術(shù)范圍,切除在于完全而不在于大范圍清掃.關(guān)鍵詞胃腫瘤;問質(zhì)瘤;外科治療中圖分類號:R735.2文獻標識碼:BSurgicaltreatmentof2astrOintestinalstromaltumorsofstomachHANXue—dong(HuaianFirstHospitalAffiliatedtONanjingMedicalUniversity.HuaianFirstPeopleSHospitai,Huaian223300,China)AbstractObjective:Toinvestigatethes
6、urgicaltreatmentofgastrOintestinalstromaltumors(GIST)ofstomach.Methods:Theclinicaldataofl9caseswithGISTofstomachwereanalyzedretrospectively.Results:Tomorswerefoundbygastroscopy.bariummealandcomputertomography.ThepreoperationaldiagnosisofGISTwasl3cases,andonly4withpathologicalevidences.GISTlo
7、catedatcardiaandgastricfundusin7cases,gastricbodyin9casesandgastricantrumin3cases.Diameteroftumorswasfrom2cmto25cm.Onlyonecasehadperigastriclymphnodemetastasis.Allcasesunderwentresection,ofwhichwedgedresectionin11cases,distalsubtotalgastrectomyin3cas一es5proximalgastrectomyin5cases,conbinedwi
8、thotherorgansresectionin3casesJmmunohistochemistrystainingshowedCD117positivein16cases,CD34positivein17cases-5casesrecurredormetastasized.Conclusion:SurgicalapprocchremainsthemajortreatmentforGISTofstomach.OperationshouldbedesignedaccordinmOtumorlo
