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1、分類號密級公開國際十進分類號（UDC）第四軍醫(yī)大學碩士學位論文雷公藤甲素抑制結(jié)腸癌細胞增殖的機制研究劉娟娟培養(yǎng)類別學歷研究生申請學位類型學術(shù)學位學科(領域)專業(yè)藥理學指導教師梅其炳教授指導教師單位藥學院藥理教研室二O一二年五月獨創(chuàng)性聲明秉承學校嚴謹?shù)膶W風與優(yōu)良的科學道德，本人聲明所呈交的論文是我個人在導師指導下進行的研究工作及取得的研究成果。盡我所知，除了文中特別加以標注和致謝的地方外，論文中不包含其他人已經(jīng)發(fā)表或撰寫過的研究成果，不包含本人或他人已申請學位或其他用途使用過的成果。與我一同工作的同志對本研究所做的
2、任何貢獻均已在論文中作了明確的說明并表示了致謝。申請學位論文與資料若有不實之處，本人承擔一切相關(guān)責任。論文作者簽名：日期：保護知識產(chǎn)權(quán)聲明本人完全了解第四軍醫(yī)大學有關(guān)保護知識產(chǎn)權(quán)的規(guī)定，即：研究生在校攻讀學位期間論文工作的知識產(chǎn)權(quán)單位屬第四軍醫(yī)大學。本人保證畢業(yè)離校后，發(fā)表論文或使用論文工作成果時署名單位仍然為第四軍醫(yī)大學。學?？梢怨颊撐牡娜炕虿糠謨?nèi)容（含電子版，保密內(nèi)容除外），可以采用影印，縮印或其他復制手段保存論文。學校有權(quán)允許論文被查閱和借閱，并在校園網(wǎng)上提供論文內(nèi)容的瀏覽和下載服務。同意學校將論文加入
3、《中國優(yōu)秀博碩士學位論文全文數(shù)據(jù)庫》和編入《中國知識資源總庫》，同意按《中國優(yōu)秀博碩士學位論文全文數(shù)據(jù)庫出版章程》規(guī)定享受相關(guān)權(quán)益。論文作者簽名：導師簽名：日期：雷公藤甲素抑制結(jié)腸癌細胞增殖的機制研究研究生：劉娟娟學科專業(yè)：藥理學所在單位：第四軍醫(yī)大學藥學院藥理教研室導師：梅其炳教授輔導教師：王志鵬副教授資助基金項目：國家973計劃前期研究專項資助項目（2010CB535002）關(guān)鍵詞：雷公藤甲素；結(jié)直腸癌；p21；ERK1/2；cyclinA1；β-catenin中國人民解放軍第四軍醫(yī)大學2012年5月第四軍醫(yī)
4、大學碩士學位論文目錄縮略語表················································································································································3中文摘要································································································
5、················································4ABSTRACT··········································································································································7前言·····························································
6、·················································································11文獻回顧··············································································································································12正文··························
7、····················································································································25實驗一雷公藤甲素對HT29細胞和SW480細胞增殖、周期、凋亡的影響····················251材料··················································································
8、···········································252方法·····························································································································263結(jié)果·········
