資源描述：
《intro 1_ computational side of computational biology.》由會(huì)員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在教育資源-天天文庫(kù)。
1、Bphys/BiolE-101=HST508=GEN224Yourgradeisbasedonsixproblemsetsandacourseproject,withemphasisoncollaborationacrossdisciplines.Opento:upperlevelundergraduates,andallgraduatestudents.Theprerequisitesarebasicknowledgeofmolecularbiology,statistics,&computing.Plea
2、sehandinyourquestionnaireafterthisclass.FirstproblemsetisduebeforeLecture3startsviaemailorpaperdependingonyoursectionTF.Harvard-MITDivisionofHealthSciencesandTechnology1HST.508:GenomicsandComputationalBiologyBio101:Genomics&ComputationalBiologyWeek#1Intro1:
3、Computing,Statistics,Perl,MathematicaWeek#2Intro2:Biology,comparativegenomics,models&evidence,applicationsWeek#3DNA1:Polymorphisms,populations,statistics,pharmacogenomics,databasesWeek#4DNA2:Dynamicprogramming,Blast,multi-alignment,HiddenMarkovModelsWeek#5R
4、NA1:3D-structure,microarrays,librarysequencing&quantitationconceptsWeek#6RNA2:Clusteringbygeneorcondition,DNA/RNAmotifs.Week#7Protein1:3Dstructuralgenomics,homology,dynamics,function&drugdesignWeek#8Protein2:Massspectrometry,modifications,quantitationofinte
5、ractionsWeek#9Network1:Metabolickinetic&fluxbalanceoptimizationmethodsWeek#10Network2:Molecularcomputing,self-assembly,geneticalgorithms,neural-netsWeek#11Network3:Cellular,developmental,social,ecological&commercialmodelsWeek#12ProjectpresentationsWeek#13Pr
6、ojectPresentationsWeek#14ProjectPresentations2Intro1:Today'sstory,logic&goalsLife&computers:Self-assemblyrequiredDiscrete&continuousmodelsMinimallife&programsCatalysis&ReplicationDifferentialequationsDirectedgraphs&pedigreesMutation&theSingleMoleculesmodels
7、BellcurvestatisticsSelection&optimality31011111111111111100000000000000111111111111111111111111111010011010011010110010110011101100101100101100110110011001111111011101111111111111111111110100110100110101100010011001011001011001011001110111001111111110111011
8、1111111111111101001101001110110010110010110010110001001101001111111111111111111111111100000000000041111111111114acgt11001111100011110155gggatttagctcagttgggagagcgccagactgaagaPost-300tgenomes&ttggag3Dstr
