資源描述:
《麝香保心丸輔助治療慢性收縮性心力衰竭(氣虛血瘀型)的臨床觀察》由會(huì)員上傳分享,免費(fèi)在線閱讀,更多相關(guān)內(nèi)容在學(xué)術(shù)論文-天天文庫(kù)。
1、中圖分類號(hào):R256.2云南中匡學(xué)院208屆攻讀碩士學(xué)位研究生學(xué)位論文麝香保心丸輔助治療劇生收縮性心力衰竭(氣虛血瘀型)的臨床觀察學(xué)院監(jiān)莊匡堂隨申請(qǐng)人姓名奎莖導(dǎo)師姓名筮倒副塑攫二oo八年五月三十日中文摘要目的:通過(guò)臨床觀察,研究麝香榘心丸輔助治療慢陛收縮№山力衰竭(氣虛血!泰型)的臨床療效。方法:按照病例納入標(biāo)準(zhǔn)選擇病例和排除病例標(biāo)準(zhǔn),采用隨機(jī)分層法把60例患者分為兩組,治療組30例,對(duì)照組30例。兩組均按照性別、年齡、病程、心功能分級(jí)、LVEF水平分別進(jìn)行矛檢驗(yàn),均無(wú)差別。將心功能為II--III級(jí),中醫(yī)辯證屬氣虛血瘀
2、證的慢性收縮性心力衰竭患者60例隨機(jī)分為西醫(yī)常規(guī)治療組30例和西醫(yī)常規(guī)治療加麝香保心丸組30例。兩組均給予利尿劑、p一受體阻滯劑、血管緊張素轉(zhuǎn)換酶抑制劑、地高辛。治療組在對(duì)照組的治療基礎(chǔ)上加用麝香保心丸2丸,~日三次,口服。治療三月觀察療效。結(jié)果:兩組治療后中醫(yī)證候療效、心功能改善均較治療前有效,總有效率分別為治療組96.6%,對(duì)照組93.3%,P>O.05,總療效無(wú)顯著差異;但治療組顯效率為60%,對(duì)照組為50%,經(jīng)卡方檢驗(yàn)P<0.05顯示有統(tǒng)計(jì)學(xué)意義,治療組顯效率優(yōu)于對(duì)照組。治療組在緩解心悸、氣短喘息、疲乏方面優(yōu)于對(duì)
3、照組P兩組均可鮪cJ,提高LVEF,縮小LVEDD,提高SV,增加CI,治療組在提高LVEF、增孤LVEDD方面優(yōu)于對(duì)照組。血液流變學(xué),兩組治療前后比較均可有效改善血粘度,治療后組間比較有統(tǒng)計(jì)學(xué)意義。治療組療效優(yōu)于對(duì)照組。提示對(duì)血瘀證療效顯著。6min步行試驗(yàn)結(jié)果顯示兩組在改善運(yùn)動(dòng)耐量有顯著療效(P<0.01),且經(jīng)t檢驗(yàn)得出治療組優(yōu)于對(duì)照組(P<0.05)。結(jié)論:應(yīng)用麝香保心丸輔助治療慢性收縮性心力衰竭較單獨(dú)應(yīng)用常規(guī)西藥治療,可更有效改善臨床癥狀,提高心功能,提高運(yùn)動(dòng)耐量,降低血液粘稠度有較好應(yīng)用價(jià)值,值得進(jìn)一步深入研
4、究。關(guān)鍵詞:麝香保心丸:慢性收縮性心力衰竭;.氣虛血瘀;I艋床觀察麝香f器I)聲晴胡!艙療嚙m15胤批山力衰竭(氣虛ln嗽型)的l劬劬吐察ClinicalobservationontheEffectoftheTreatmentofChronicContractilityHeartFailure0PatientswiththeinterventionofShexiangBaoxinpillsPostgraduate:QinLi(withmajorofInternalMedicineofTCM)Directedby:Asso
5、ciateProfessorLiZhangAbstractobjective:ToobservetheclinicaleffectivenessofthetreatmenttoChronicContractilityHeartFailure-(bloodstasisandvitalenergyasthenia)PatientscombiningtheinterventionofShexiangBaoxinpills.Methods:60caseswithchroniccontractilityheartfailurewe
6、rerandomlydividedintotwogroups:treatmentgroup(30cases)orcontrolgroup(30cases).Twogroupsarenotdifferentinages,levelofLVEFaccordingtochi-aquaretest.Twogroupstookhydragogue,ACEI—inhibitors,fl--blockers,digoxin.TreatmentgroupreceivedroutinetreatmentalongwithtakingShe
7、xiangBaoxinpills,atdosageoftwopillsperday.Thecourseisthreemonths.Results:Therateofthetotaleffectivenessofthetreatmentgroupwas96.6%andtherateofthecontrolgroupwas93.3%.Thecomparisonbetweenthetwogroupsshowedindifferences尸>0.05.Valideffectrateofthetreatmentgroupwas60
8、%,thecontrolgroupwas50%,thecomparisonbetweenthetwogroupsshowedsignificantdifferences,P<0.05.Thetreatmentgroupwasbetterthanthecontrolgroup.Thetwogroups’symptoms