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1、2018屆碩士學(xué)位論文NO2對肺上皮細(xì)胞侵襲轉(zhuǎn)移的影響及其機制研究作者姓名張舒婕指導(dǎo)教師桑楠教授學(xué)科專業(yè)環(huán)境生物醫(yī)學(xué)研究方向環(huán)境毒理學(xué)培養(yǎng)單位環(huán)境與資源學(xué)院學(xué)習(xí)年限2015年9月至2018年6月二〇一八年六月山西大學(xué)2018屆碩士學(xué)位論文NO2對肺上皮細(xì)胞侵襲轉(zhuǎn)移的影響及其機制研究作者姓名張舒婕指導(dǎo)教師桑楠教授學(xué)科專業(yè)環(huán)境生物醫(yī)學(xué)研究方向環(huán)境毒理學(xué)培養(yǎng)單位環(huán)境與資源學(xué)院學(xué)習(xí)年限2015年9月至2018年6月二〇一八年六月ThesisforMaster’sdegree,ShanxiUniversity,2018TheToxicologicalEff
2、ectandMolecularMechanismofNO2onEpithelialCellMetastasisStudentNameShujieZhangSupervisorProf.NanSangMajorEnvironmentBiologicalMedicineSpecialtyEnvironmentalToxicologyDepartmentCollegeofEnvironmentandResourceResearchDuration2015.09-2018.06June,2018目錄中文摘要........................
3、.................................................................................................IABSTRACT......................................................................................................................III第一章文獻綜述..........................................
4、......................................................................11.1NO2污染現(xiàn)狀以及相關(guān)健康風(fēng)險........................................................................11.1.1NO2污染現(xiàn)狀.............................................................................................11.1.2NO2
5、對肺的毒性效應(yīng).................................................................................31.2肺上皮細(xì)胞侵襲遷移機制...................................................................................41.2.1上皮-間質(zhì)轉(zhuǎn)化(EMT)........................................................................
6、..41.2.2細(xì)胞外基質(zhì)(ECM)...............................................................................51.3本課題的提出及意義...........................................................................................6第二章NO2吸入誘導(dǎo)小鼠肺組織上皮-間質(zhì)轉(zhuǎn)化及MAGL抑制的保護作用.............72.1引言.....................
7、..................................................................................................72.2材料與方法...........................................................................................................82.2.1實驗材料與儀器.................................................
8、.......................................82.2.2實驗動物分組與處理..............