基于ewod的數(shù)字微流控器件-研究

基于ewod的數(shù)字微流控器件-研究

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時間:2019-03-08

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1、AbstractAbstractInrecentyears,theemergingdigitalmicrofluidictechnologyhasshownhugedevelopmentpotentialandapplicationprospectinchemistry,biology,medicineandotherareasbecauseofitsadvantageofsimplestructure,savingthesample,easeofintegration,widemanipulaterangeandsoon.Thisdissertationha

2、spreliminarilydiscussedthedigitalmicrofluidictechnologythroughthemethodoftheoreticalanalysis,simulationoptimizationandexperimentalverification.Firstly,thedissertationanalyzedtheadvantagesanddisadvantagesofvariouscontrolmethodofdigitalmicrofluidicsystem,andthen,determinedtoutilizethe

3、theoryofelectrowettingondielectric(EWOD)torealizethemicrodroplet’sdriven.Afterwards,thedissertationintroducedtheprincipleofEWOD,establisheditsmathematicalmodelandsimulatedtheprocessofEWOD.Furthermore,thedissertationexpoundedhowtoimplementthemicrodroplet’sdrivenusingthetheoryofEWODin

4、detail.Secondly,thedissertationdevelopedamathematicmodelofthedigitalmicrofluidicsystem,simulatedthestaticanddynamicperformanceofthesystemwiththeuseofCOMSOLMultiphysics4.4,obtainedtheelectricpotentialdistributionofthesystem,analyzedtheinfluenceoftheparameterssuchasthethicknessofdiele

5、ctriclayertothedigitalmicrofluidicchip,andthenprovedthatthesingleplatestructurewaseasiertodrivethedroletthanthedoubleplatesructure.Aferwards,thedissertationsimulatedthemicrodroplet’smovementprocessonthepremiseofthedeterminedstructureandparameters.Thusitprovidedareliableguidefortheop

6、timizationofthechip.Finally,accordingtothesystemstructureandparametersdeterminedbyoursimulations,weproducedadigitalmicrofluidicchip,usingthemethodofwetetchingprocesstomaketheITOdriveelectrode,usingthemethodofRFmagnetronsputteringtodepositetheSiO2dielectriclayer,andusingCH3(CF2)7(CH2

7、)2Si(OC2H5)3toproducethehydrophobiclayer.Wealsodiscussedthekeytechnologyandinfluencefactorsinthechipproductionprocess.Then,wedesignedandweldedcontrolcircuitofthedigitalmicrofluidicsystem,andalsoverifieditsfunction.Afterthat,wesetupatestplatformfordigitalmicrofluidicsystemandrealized

8、thetransportofmicro

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