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1、SCIENCEAnnuAlReview2009JeanCui(center)andherlaJollalaboratoriesteamarepioneeringnewapproachestonon-smallcelllungcancer.3findvideosofJeAnCuiAndotheRsCientistsAtpfizeR.Com/AnnuAlWebringthebestscientificmindstogethertochallengethemostfeareddiseasesofourtime…lungcancer
2、cells,asseenhereandonthecover,aredifficulttokill,andstandardchemotherapybringsharshsideeffects.onepotentialnewapproachappearstoavoidthoseeffectsandhasshowedsuchpromisethatithasbeenexpeditedtophaseiiitrials.martinBrennerandhisteamareworkingonanapproachtotreatdiabete
3、sbyregrowingpancreaticcells.bychartinganeWcourseinbiomedicalresearch…auniquemodelourapproachtodiscoveringandIntermsofaccountability,thisdevelopingnewmedicinesandapproachdistinctlyclarifieswhoisforScientificvaccines.Biomedicalresearchatresponsibleforeachsequenceinth
4、ePfizerisnoworganizedintotwomultiyear,billion-dollar-plusmarchachievementcollaborative,highlyfocusedunits,fromscientifictheorytoapproved,PharmaTherapeuticsR&Dandprescribedmedicineorvaccine.BioTherapeuticsR&D.EachoftheseThetworesearchunitseachhaveunitsmarshalstheres
5、ourcestotheresponsibilitytobringforwardpursueandprovetheoriesaboutsufficientnumbersofpotentialhoweithersmall-moleculechemicalmedicinesandvaccinestosustaincompoundsorlarge-molecule,Pfizer’sgrowth.Thecustomer-facingprotein-basedbiologicsmightbusinessunitshavetherespo
6、nsibilitypreventorchangethecourseofaformovingmoleculesthataredisease.Atthepointof“proofofproveninconceptthroughtheIt’softensaidthathumanitywillconcept,”thepotentialnewmedicinemid-to-latestagesofclinicaltrialsmakemorebiomedicalprogressorvaccineistransferredtoonetoco
7、mmercialization.Ournewinthenext20yearsthanintheofPfizer’scustomer-facingbusinessmodeltomanagethissequenceprevioustwothousand.Behindthatgroupsforlarge-scaleclinicaltrials,makescertainthatthereisstrongstatementisacomplexquestion.registrationandcommercialization.agree
8、mentbetweenresearchandWithsomuchnewsciencetoThekeywordsforthisapproachcommercialgroupsonwhattoputpursue,howdoesacompanylikearefocusandaccountabil