雙氫睪酮對ad所致mci期samp8雄性小鼠空間學(xué)習(xí)記憶及海馬突觸可塑性的影響

雙氫睪酮對ad所致mci期samp8雄性小鼠空間學(xué)習(xí)記憶及海馬突觸可塑性的影響

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雙氫睪酮對ad所致mci期samp8雄性小鼠空間學(xué)習(xí)記憶及海馬突觸可塑性的影響_第1頁
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1、授予單位代碼10089學(xué)號或申請?zhí)?0U1069HebeiMedicalUniversity博士學(xué)位論文科學(xué)學(xué)位雙氫睪酮對AD所致MCI期SAMP8雄性小鼠空間學(xué)習(xí)記憶及海馬突觸可塑性的影響研究生:潘文森導(dǎo)師:崔慧先教授專業(yè):人體解剖與組織胚胎學(xué)2015年4月河北醫(yī)科大學(xué)學(xué)位論文使用授權(quán)及知識產(chǎn)權(quán)歸屬承諾本學(xué)位論文在導(dǎo)師(或指導(dǎo)小組)的指導(dǎo)下,由本人獨立完成。本學(xué)位論文研究所獲得的研究成果,其知識產(chǎn)權(quán)歸河北醫(yī)科大學(xué)所有。河北醫(yī)科大學(xué)有權(quán)對本學(xué)位論文進行交流、公幵和使用。凡發(fā)表與學(xué)位論文主要內(nèi)容相關(guān)

2、的論文,第一署名為單位河北醫(yī)科大學(xué)’試驗材料、原始數(shù)據(jù)、申報的專利等知識產(chǎn)權(quán)均歸河北醫(yī)科大學(xué)所有。否則,承擔(dān)相應(yīng)法律責(zé)任。研究生簽名導(dǎo)師簽章:?級學(xué)院領(lǐng)導(dǎo)蓋章:河北醫(yī)科大學(xué)研究生學(xué)位論文獨創(chuàng)性聲明本論文是在導(dǎo)師指導(dǎo)下進行的研究工作及取得的研究成果,除了文中特別加以標(biāo)注和致謝等內(nèi)容外,文中不包含其他人已經(jīng)發(fā)表或撰寫的研究成果,指導(dǎo)教師對此進行了審定。本論文由本人獨立撰寫,文責(zé)自負。導(dǎo)師簽章研究生簽名:目錄中文摘要············································

3、··························································1英文摘要····································································································10英文縮寫··················································································

4、··················22研究論文雙氫睪酮對AD所致MCI期SAMP8雄性小鼠空間學(xué)習(xí)記憶及海馬突觸可塑性的影響引言····································································································24第一部分雙氫睪酮對AD所致MCI期SAMP8雄性小鼠空間學(xué)習(xí)記憶的影響前言···············································

5、·····················································28材料與方法························································································30結(jié)果···································································································

6、·33附圖····································································································35附表····································································································39討論······································

7、······························································40小結(jié)····································································································44參考文獻···············································································

8、·············45第二部分雙氫睪酮對AD所致MCI期SAMP8雄性小鼠海馬突觸可塑性相關(guān)蛋白SYN、PSD-95、Drebrin表達的影響前言····································································································49材料與方法···························································

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