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1、ThisisanopenaccessarticlepublishedunderanACSAuthorChoiceLicense,whichpermitscopyingandredistributionofthearticleoranyadaptationsfornon-commercialpurposes.Reviewpubs.acs.org/CRClassi?cationofIntrinsicallyDisorderedRegionsandProteins,?,??,▲?,▲?,▲RobinvanderLee,*MarijaBuljan,Benjami
2、nLang,RobertJ.Weatheritt,§∥⊥#?GaryW.Daughdrill,A.KeithDunker,MonikaFuxreiter,JulianGough,JoergGsponer,○◆,?,⊕?∥&DavidT.Jones,PhilipM.Kim,RichardW.Kriwacki,ChristopherJ.Old?eld,RohitV.Pappu,@,$%,★□,?PeterTompa,VladimirN.Uversky,PeterE.Wright,andM.MadanBabu*?MRCLaboratoryofMolecular
3、Biology,FrancisCrickAvenue,CambridgeCB20QH,UnitedKingdom?CentreforMolecularandBiomolecularInformatics,RadboudUniversityMedicalCentre,6500HBNijmegen,TheNetherlands§DepartmentofCellBiology,Microbiology,andMolecularBiology,UniversityofSouthFlorida,3720SpectrumBoulevard,Suite321,Tamp
4、a,Florida33612,UnitedStates∥DepartmentofBiochemistryandMolecularBiology,IndianaUniversitySchoolofMedicine,Indianapolis,Indiana46202,UnitedStates⊥MTA-DEMomentumLaboratoryofProteinDynamics,DepartmentofBiochemistryandMolecularBiology,UniversityofDebrecen,H-4032Debrecen,Nagyerdeikrt9
5、8,Hungary#DepartmentofComputerScience,UniversityofBristol,TheMerchantVenturersBuilding,BristolBS81UB,UnitedKingdom?DepartmentofBiochemistryandMolecularBiology,CentreforHigh-ThroughputBiology,UniversityofBritishColumbia,Vancouver,BritishColumbiaV6T1Z4,Canada○B(yǎng)ioinformaticsGroup,De
6、partmentofComputerScience,UniversityCollegeLondon,London,WC1E6BT,UnitedKingdom◆?⊕TerrenceDonnellyCentreforCellularandBiomolecularResearch,DepartmentofMolecularGenetics,andDepartmentofComputerScience,UniversityofToronto,Toronto,OntarioM5S3E1,Canada?DepartmentofStructuralBiology,St
7、.JudeChildren’sResearchHospital,Memphis,Tennessee38105,UnitedStates&DepartmentofBiomedicalEngineeringandCenterforBiologicalSystemsEngineering,WashingtonUniversityinSt.Louis,St.Louis,Missouri63130,UnitedStates@VIBDepartmentofStructuralBiology,VrijeUniversiteitBrussel,Brussels,Belg
8、ium$InstituteofEnzymology,ResearchCentre
