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《The systemic toxicity of heavy metal mixtures in重金屬混合物的系統(tǒng)毒性 胡扯》由會(huì)員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在學(xué)術(shù)論文-天天文庫(kù)。
1、ToxicologyResearchViewArticleOnlinePAPERViewJournal
2、ViewIssueThesystemictoxicityofheavymetalmixturesinratsCitethis:Toxicol.Res.,2018,7,396aaabaSamuelSelormFiatiKenston,?HongSu,?ZhouLi,?LuKong,YafeiWang,aaccaXinSong,YuanliangGu,TabathaBarber,JoniAldinger,QihangHua,aca,
3、ca,dZhenLi,MinDing,JinshunZhao*andXialuLin*Toexplorethehealthe?ectsofmulti-heavymetalexposure,SpragueDawley(SD)ratswereorallygivenonedoseofheavymetalmixtures(HMMs).TheeightmostcommondetectableheavymetalsinNingboareaarezinc(Zn),copper(Cu),manganese(Mn),chromium(Cr),nic
4、kel(Ni),cadmium(Cd),lead(Pb)andmercury(Hg).Inthisstudy,mixturesoftheseeightheavymetalswerepreparedusingthecompoundszincsulfateheptahydrate,cupricsulfate,manganesedichloride,potassiumdichromate,nickeldichloride,cadmiumdichloride,leadacetate,andmethylmercurychloridewith
5、ionmassproportionsof1070.0,312.6,173.1,82.6,30.0,13.3,6.6,and1.0,respectively.Theratswererandomlydividedintofourgroups.CreativeCommonsAttribution-NonCommercial3.0UnportedLicence.Besidethecontrolgroup,eachratreceivedacorrespondingdoseofHMMs215,464or1000mgperkgbodyweigh
6、t(bwt),respectively.Theratswereobservedfor4weeks.Duringthelastweekofobservation,theMorriswatermazetestwasusedtoinvestigatespatiallearningandmemoryinthetreatedrats.Theratswereexsanguinatedundercompletechloralhydrateanesthesiaandorgancoe?cientsweremeasured.Biochemicalte
7、stsofbloodandserumsampleswerecarriedout.TheresultsshowedReceived29thSeptember2017,abnormalitiesinthehematologicalsystem,decreasedrenalfunction,hepaticinjuryanddisturbancesinAccepted14thDecember2017theelectrolytebalanceoftheratstreatedwithahighdoseofHMMs.Deathofsomerat
8、swasalsoDOI:10.1039/c7tx00260bobserved.Thispaperanalyzedhowaone-timehighdoseoraladministrationofHMMsinducedsystemicThisarticleislicensedunderarsc.li/toxicology-researchtoxicity.OpenAccessArticle.Publishedon29January2018.Downloadedon8/6/201810:06:06AM.1.Introductionthr
9、oughwastedisposalmachineriesintheformofmetalfumesofsuspendedparticulates.SometraceamountsofheavyHeavymetalsarehighdensityele
