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1、Proc.Natl.Acad.Sci.USAVol.95,pp.4816±4821,April1998EngineeringEngineeringanalysisofbiologicalvariables:Anexampleofbloodpressureover1day(FourierspectrumyHilbertspectrumyGumbelextreme-valuestatisticsypulmonaryartery)WEIHUANG*,ZHENGSHEN2,NORDENE.HUANG3§,ANDYUANCHENGFUNG*?*DepartmentofBioengineering,U
2、niversityofCalifornia,SanDiego,LaJolla,CA92093-0412;Divisionsof2EngineeringScienceand§EngineeringandAppliedScience,CaliforniaInstituteofTechnology,Pasadena,CA91125;and3LaboratoryforHydrosphericProcesses,OceanandIceBranch,NationalAeronauticsandSpaceAdministrationGoddardSpaceFlightCenter,Greenbelt,M
3、D20771ContributedbyYuanChengFung,February20,1998ABSTRACTAlmostallvariablesinbiologyarenonsta-MATERIALSANDEXPERIMENTALMETHODStionarilystochastic.Forthesevariables,theconventionaltoolsForthepurposeoflongtermrecordingofbloodpressure,aleaveusafeelingthatsomevaluableinformationisthrowncathetermustbeimp
4、lantedintoanartery.TheRiva±Rocciawayandthatacomplexphenomenonispresentedimpre-cuffinflationmethodofbloodpressuremeasurementbasedoncisely.Here,weapplyrecentadvancesinitiallymadeintheKorotkoffsoundscannotprovidethedesireddata.WestudiedstudyofoceanwavestostudythebloodpressurewavesintheadultmaleSpragu
5、e±Dawleyratsunderaprotocolapprovedbylung.Wenotefirstthat,inalongwavetrain,thehandlingoftheUniversityofCalifornia,SanDiegoCommitteeonAnimalthelocalmeanisofpredominantimportance.ItisshownthatResearch.RatspurchasedfromHarlan±Sprague±Dawleywereasignalcanbedescribedbyasumofaseriesofintrinsicmodegiven3±
6、7daystoacclimatizetotheirhousing.Housingtem-functions,eachofwhichhaszerolocalmeanatalltimes.Theperaturewascontrolled(70°Fy72°F)anda12:12hlight±darkprocessofderivingthisseriesiscalledthe``empiricalmodecyclewasimposedat0600and1800h.Theyhadcontinuousdecompositionmethod.''Conventionally,Fourieranalysi
7、saccesstostandardratchow(Harlan±Sprague±Dawley)andrepresentsthedatabysineandcosinefunctions,butnotapwater.instantaneousfrequencycanbedefined.Inthenewway,theDuringtheimplantationofthepressureprobe,theratmustdataar
