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1、SwineHealthManagementFactsheet豬群健康管理技術(shù)實錄EIHJQ肉52治Id目(?hinii(an;KhIanSwinePiujeclGlassersDisease發(fā)性漿膜炎關(guān)節(jié)炎)Dr.JimFairies范如杰博士格萊西氏?。ㄘi多HerdHealthSpecialist動物健康專家ChinaCanadaAnimalHealthInitiative中加動物健康啟動項目Tel:010-64651512Fax:010-64651357E-mail電子信箱:iimjkvvet.comGlassersDiseaseiscausedbythebacterium
2、Haemophilusparasuis,asmallorganism,ofwhichthereareatleastfifteendifferenttypes.Itisubiquitous,foundthroughouttheworldandispresenteveninhighhealthherds.IfsuchherdsaresetupusingSPForMEWtechniquesandarefreefromHpsitcanbedevastatingwhentheyfirstbecomecontaminated,producingananthrax-1ikediseasewi
3、thhighmortalityinsows.SomeStreporganismsmaybeinvolvedaswell.?格萊西氏病是由一種稱為豬副嗜血桿菌的細菌引起的。這種細菌至少有15種血清型,世界各地均有分布,即便在高度健康的豬群中也有存在。采用無特定病原(SPF)或用藥物早期斷奶(MEW)技術(shù)而沒有豬副嗜血桿菌污染的豬群,如果感染到這種細菌的話,后果會相當嚴重,會爆發(fā)類似炭疽的疾病,在母豬群造成很高的死亡率。同時還會伴隨一些鏈球菌的感染。Inthemajorityofherdsinwhichthebacteriumisendemic,sowsproduceastrong
4、matemalimmunitywhichnormallypersistsintheiroffspringuntil8to12weeksofageandasaresult,theeffectsoftheinfectioninweanersareusuallynilorveryminimal.Thepigsbecomesub-clinicallyinfectedwhenstillprotectedandthenstimulatetheirownimmuneresponse.Ifhoweverthematernalimmunitywearsoffbeforetheybecomeinf
5、ectedtheymaydevelopseveredisease.Itcanhoweverbecomeasecondaryorganismwherethereareothermajorpathogensandinparticularenzooticpneumonia.Outbreaksofdiseasearesometimesexperieneedinsuckingpigs,particularlyingiltherds.這種病菌在大部分豬群屮都是木地性的。母豬分娩時為新生仔豬提供了很強母源免疫,仔豬體內(nèi)的母源抗體通??梢跃S持到8至12周齡。因此,這種病原對斷奶階段的仔豬影響不
6、人或沒有影響。隨母源抗體水平下降,仔豬仍然受到母源抗體-定程度的保護,此時會出現(xiàn)亞臨床感染,仔豬自身的免疫應(yīng)答反應(yīng)將被激活,從而保證以后免得這種疾病。但是,如果仔豬在母源抗體完全消失Z后才感染到這種病原,就會出現(xiàn)嚴垂病情。這種細菌也會作為繼發(fā)感染的病原伴隨其它主要病原混合感染,尤其是有地方性豬肺炎存在時。這種病在哺乳仔豬群尤其是青年母豬中偶有爆發(fā)。Clinicalsigns臨床癥狀Peracutedisease(Naiveherd)特急性病(未經(jīng)病原感染群)Thediseasecreatesadevastatingacutemeningitis.Thisisnormallyse
7、enwhenanaiveadultisintroducedtoanormalherd.Within48hourstheadultdemonstrateseverepneumonia,depression,anorexia,highrectaltemperature42C.Terminallytheanimaldemonstratesincoordination,prostration,meningitisanddies.Deathcanoccurveryquicklyafterarrival