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1、88PosterSession-ItheNDandnon-NDgroupswithregardstoage,sex,diagnosisandsigni?cantcauseofmorbidityamongimmuncompromisedpatientsconditioningregimen,orthenumberofdaystoresolutionofneutro-inthehospitalsetting.Further,suchpatientstendtoseroconvertin-penia.Therewerenosigni?cantdifferencesinth
2、enumberofposi-ef?cientlyandwithsuboptimaltitersfollowingprophylacticvaccina-tiveculturesbetweenthegroupsduringtheneutropenicperiod.tionwitheitherthestandardorrecombinantin?uenzavaccines.However,aftertheresolutionofneutropenia,therewasasigni?-Towardthegoalofaddressingthisissue,wehavedev
3、elopedaninvi-cantlyhighernumberofnon-entericgram-positivecoccalinfectionstromodelofdendriticcell(DC)immunotherapyutilizingDCsgen-intheNDgroupcomparedtonon-ND.Therewasalsoatrendto-eratedfromumbilicalcordblood(UCB).wardsahigherincidenceofCdif?cile,andasigni?cantlyhigherin-Methods:UCBmono
4、cyteswereharvestedbyadherence,andcidenceofnewpositivesurveillanceculturesofVREonrectalswabsUCBDCsweregeneratedbyincubationinGM-CSFandIL-4.Im-intheNDgroup.matureDCswereloadedwithpuri?edrHAprotein[A/NewCaledo-Our?ndingsshowthatthereisnoapparentbene?tassociatedwithnia(H1N1)],maturedwithan
5、in?ammatorycytokinecocktail,andND.However,moresurprisingisthe?ndingthatsomeinfectionsusedtostimulateautologousT-lymphocytes.T-lymphocyteprim-weremorecommonwithND.Itcouldbespeculatedthatthemicro-inganddevelopmentweresupportedbysupplementationwithbialcontentofthenon-NDishigherand,inthese
6、ttingofbroad-IL-12,IL-2,IL-7,andIL-15.DCandT-cellswereanalyzedbyspectrumantimicrobialprophylaxisandtherapy,suchadietcould?owcytometry.Antigenspeci?cresponsesweredocumentedby51contributetoreducedcolonizationwithvirulentmicroorganisms.IFN-gELISpot,Crlysis,andtetramerstaining.RecombinantT
7、hese?ndingssuggestthatadditionalstudiesareneededtoinvesti-hemagglutininHLA-restrictedpeptidesweresynthesizedbygatetheroleofdietaryrestrictions.Ifour?ndingsarecon?rmed,Sigma-Genosys(TheWoodlands,Texas).MHCclassIIDR15-amajorchangeinanestablishedbutnon-evidence-basedpracticerestrictedte
