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《阿托伐他汀對急性腦梗死患者神經(jīng)功能康復的作用及頸動脈內(nèi)膜厚度的影響.pdf》由會員上傳分享,免費在線閱讀,更多相關內(nèi)容在應用文檔-天天文庫。
1、中國實用神經(jīng)疾病雜志2014年7月第17卷第14期ChineseJournalofPracticalNervousDiseasesJu1.2014Vo1.17No14·9·阿托伐他汀對急性腦梗死患者神經(jīng)功能康復的作用及頸動脈內(nèi)膜厚度的影響胡冰凌四川巴中市中心醫(yī)院神經(jīng)內(nèi)科巴中636000【摘要】目的研究阿托伐他汀(ATVT)對急性腦梗死(ACI)患者神經(jīng)功能(NF)康復的作用以及頸動脈內(nèi)膜中層厚度(IMT)的影響。方法將我院2010-08-2013-08入院就診的122例ACI病患隨機分成2組,對照組給予常規(guī)治療,觀察組在此基礎上加用ATVT。觀察2組患者治療前后
2、神經(jīng)功能缺損程度(Nervefunctiondamagedegree,NFDD)、IMT變化以及療效。結(jié)果觀察組治療后NFDS評分、頸動脈IMT均顯著小于治療前及對照組治療后,差異均具有統(tǒng)計學意義(均P<0.05)。觀察組基本痊愈率、總有效率均顯著高于對照組;觀察組病死率顯著低于對照組,差異均具有統(tǒng)計學意義(均P<0.05)。結(jié)論AVTV治療ACI療效顯著,能有效促進患者NF康復,降低頸動脈IMT,值得臨床推薦。【關鍵詞】阿托伐他??;急性腦梗死;神經(jīng)功能;動脈內(nèi)膜厚度【中圖分類號】R743.33【文獻標識碼】A【文章編號】1673—5110(2014)14-00
3、09—03Effect0fatorvastatinonnervefunctionrehabilitatiOnandcarotidintimamediathicknessinpatientswitha-cutecerebralinfarctionH“BinglingDepartmentofNeurology,theCentralHospitalofBazhong,Bazhong636000,China[Abstract]0bjectiveTosudytheeffectofatorvastatinonnervefunctionrehabilitationandcar
4、otidintimamediathicknessinpatientswithacutecerebralinfarction.Methods122casesofpatientswithacutecerebralinfarctioninourhospitalfromAug2010toAug2013wererandomlydividedintotWOgroups.Thecontrolgroupwasgivenconventionaltreatment:theobservationgroupwasaddedwithatorvastatin.Thedegreeofnerv
5、efunctiondamage,carotidintimamediathickness(IMT)andtheeffec—tivenessoftwogroupsbeforeandaftertreatmentwerecompared.ResultsNFDSscore.carotidIMToftheobservationgroupaftertreatmentweresignificantlylessthanthosebeforetreatmentandthoseofthecontrolgroupaftertreatment,thediffer—encesweresta
6、tisticallysignificant(P<0.05).Theobservationgroup'sbasicrecoveryrateandtotalefficiencywerehigherthanthoseofthecontrolgroup;theobservationgrou~smortalitywassignificantlylowerthanthatofthecontrolgroup,thediffer—enceswerestatisticallysignificant(P<0.05).ConclusionAtorvastatinhasagoodeff
7、ectonpatientswithacutecerebralin-farction,whichcaneffectivelypromotetherehabilitationofpatientswithNF。reducetheIMTofcarotidartery.Itisworthyofrecommendingclinically.[Keywords]Atorvastatin;Nervefunctionrehabilitation;Carotidintimamediathickness;Acutecerebralinfarction;Effect隨著近年人口老齡化的
8、加劇,腦血管疾病(cer