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1、2012年8月1日第8期中醫(yī)學(xué)報第27卷總第171期No.81Aug.2012CHINAJOURNALOFCHINESEMEDICINEVo1.27SerialNo.171木香順氣丸治療惡性腹腔積液腹脹的臨床研究ClinicalStudyoRMuxiangShunqiPillsintheTreatmentofAbdominalDistensionofMalignantSeroperitoneum崔虎軍CuiHujun牡丹江醫(yī)學(xué)院附屬紅旗醫(yī)院,黑龍江牡丹江157011HongqiHospitalofMudanjiangMedicalColle
2、ge,Mudanjiang,Heilongjiang,China157011摘要:目的:探討木香順氣丸治療惡性腹腔積液患者腹脹的臨床療效。方法:將31例惡性腹腔積液腹脹患者分為治療組16例和對照組15例。治療組口服木香順氣丸6g,每日3次;對照組口服枸櫞酸莫沙必利分散片5mg,每日3次,2周為1個療程。治療后觀察兩組腹脹改善情況及兩次腹腔穿刺引流間隔時間。結(jié)果:治療組有效率為75.00%,對照組有效率為66.67%,差異無統(tǒng)計學(xué)意義(P>0.05),治療組與對照組間隔時間分別為(9.63±3.05)d和(7.27±2.81)d,治療組優(yōu)于對
3、照組,差異有統(tǒng)計學(xué)意義(P<0.05)。結(jié)論:木香順氣丸治療惡性腹腔積液患者腹脹療效顯著。Abstract:Objective:ToobservethecurativeefectsofMuxiangShunqiPillsinthetreatmentofabdominaldistensionofmalignantsero—peritoneum.Methods:31patientswithmalignantseroperitoneumwererandomlydividedintothetreatmentgroup(16cases)andthec
4、on-trolgroup(15cases).ThetreatmentgroupwasvenoraladministrationofMuxiangShunqiPillsof6g,threetimesadayfor2weeks;thec0ntrolgroupwasgivenoraladministrationofMosaprideCitrateTablets5mg.threetimesadayfor2weeks.Theimprovementsitua-tionofabdominaldistensionandtheintervaltimeofab
5、dominalparacentesisdrainagefortwotimesinbothgroupswereobservedanertreatment.Resuhs:Theefectiverateofthetreatmentgroupandthecontrolgroupwas75.O0%and66.67%respectively,andthediferencehadnostatisticalsignificance(P>0.05):Theintervaltimeofthetreatmentgroupandthecontrolgroupwas
6、(9.63±3.05)daysand(7.27±2.81)daysrespectivelyandthedifferencehadstatisticalsignificance(P<0.05).Conclusion:MuxiangShunqiPillshasgreatcurativeefectsonthetreatmentofabdominaldistensionofmalignantseroperitoneum,andisworthapplyingextensively:關(guān)鍵詞:惡性腹腔積液;腹脹;木香順氣丸;枸櫞酸莫沙必利分散片Keywo
7、rds:malignantseroperitoneum;abdominaldistension;muxiangshunqipills;mosapridecitratetablets中圖分類號CLCnumber:R256.33文獻標識碼Documentcode:A文章編號ArticleID:1674—8999(2012)08—0999一O2惡性腹腔積液的治療方法雖然很多,但療效有限。患者H20031110)每次5nag,每日3次,均以2周為1個療程。平均生存期4個月,1a生存率<10%¨J。對大多數(shù)患者而1.3療效判定標準言,緩解癥狀仍為主要
8、治療目的。惡性腹腔積液患者常出現(xiàn)顯效:腹脹消失,或矢氣次數(shù)為用藥前1倍或1倍以上;腹脹、乏力、食欲下降、腹痛、便秘和呼吸短促等癥狀,特別是有效:腹脹好轉(zhuǎn)或矢氣次數(shù)增加;無效:腹脹