資源描述：
《實(shí)時(shí)超聲造影在肝癌射頻消融治療效果評(píng)價(jià)中的應(yīng)用研究-論文.pdf》由會(huì)員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在應(yīng)用文檔-天天文庫。
1、現(xiàn)代醫(yī)學(xué)2014M，Aug；42(8)：876．879·876·odernMedicalJournal’??！??！ふ撝ほ蘴實(shí)時(shí)超聲造影在肝癌射頻消融117：1I效果評(píng)價(jià)中的應(yīng)用研究沈神，張煒煒，邱君斕，蔣智明，周鐵(南京大學(xué)醫(yī)學(xué)院附屬鼓樓醫(yī)院外科超聲室，江蘇南京210008)[摘要]目的：探討肝癌射頻消融(radiofrequencyablation，RFA)后實(shí)時(shí)超聲造影(contrast’enhancedultrasound，CEUS)對(duì)判斷治療效果的臨床應(yīng)用價(jià)值。方法：對(duì)經(jīng)RFA治療的205例肝癌患者205個(gè)病灶術(shù)后1個(gè)月
2、分別進(jìn)行常規(guī)超聲和低機(jī)械指數(shù)(MI<1．0)CEUS檢查(造影劑為SonoVue)，比較分析常規(guī)超聲與CEUS在評(píng)價(jià)肝癌射頻消融效果及局部復(fù)發(fā)中的應(yīng)用價(jià)值。所有患者均同期行增強(qiáng)cT或增強(qiáng)MRI檢查。結(jié)果：常規(guī)超聲檢查提示92個(gè)痛灶(44．9％)周邊出現(xiàn)低回聲區(qū)，或于痛灶局部檢及血流信號(hào)，常規(guī)超聲判斷消融不全或局部復(fù)發(fā)的敏感性為77．5％，特異性為76％；CEUS檢查提示80個(gè)病灶(39．0％)于動(dòng)脈期可見造影劑局部充填，CEUS判斷消融不全或局部復(fù)發(fā)的敏感性為97．5％，特異性為98．4％。結(jié)論：與常規(guī)超聲比較，CEUS可以更準(zhǔn)確判
3、斷RFA術(shù)后消融程度及局部復(fù)發(fā)情況，與增強(qiáng)CT／MRI相當(dāng)，可為射頻治療術(shù)后療效的判斷提供可靠的影像學(xué)依據(jù)。[關(guān)鍵詞]實(shí)時(shí)超聲造影；肝臟腫瘤；射頻消融[中圖分類號(hào)]R735．7；R730．41[文獻(xiàn)標(biāo)識(shí)碼]A[文章編號(hào)]1671。7562(2014)08—0876。04doi：10．3969／i．issn．1671—7562．2014．08．010Clinicalapplicationofreal。timecontrast。enhancedultras0n0graphyforlivercancerassessmentafterrad
4、iofrequencyablationSHENYi，ZHANGWei。wei，QIUJun。lan，JIANGZhi。ming，ZHOUTie(DepartmentofSurgicalUltrasound，theAfiliatedDrumTowerHospitalofngUniversityMedicalSchool，№ng210008，China)[Abstract]0bjective：Toinvestigatetheclinicalvalueofreal—timecontrast。enhanceduhrasonography(C
5、EUS)inevaluatingthetherapeuticefficacyofradiofrequencyablation(RFA)forlivertumor．Methods：205lesionsof205HCCpatientswereexaminedbybothconventionalultrasoundandreal—timeCEUS(SonoVue，MI<0．1)onemonthafterRFA．DifferencesbetweenconventionalultrasoundandCEUSwerecomparedineval
6、uatingthetherapeuticefficacyandlocalrecurrence．Alllesionswereconfirmedbycontrast‘enhanceCTorMRIscanatthesametime．Results：ConventionalultrasoundfoundlOWechoareasaroundorbloodinflowsinside92lesions(44．9％)．Thesensitivityandspecifityofconventionalultrasoundwere77．5％and76％r
7、espectively．CEUSfoundthat80lesions(39％)presentedpartialcontrastenhancementonarterialphase．Thesensitivityandspecifityofconventionalultrasoundwere97．5％and98．4％respectively．Conclusion：CEUSismoreaccurateinidentifyingthecompletenessofablationandlocalrecurrenceafterRFA，provi
8、dingareliablemodalityinevaluating[收稿日期]2014一O1_08[修回日期]2014—06—24[作者簡介]沈稀(1981一)，男，江蘇南通人，住院醫(yī)師。E‘mail：syps2@sina．coal[
