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1、.--——482.——介入放射學(xué)雜志2014年6月第23卷第6期JInterventRadiol2014.Vo1.23.No.6·非血管介入Non—vascularintervention·超聲造影在肺周占位穿刺活檢的應(yīng)用價(jià)值王凇,楊薇,張暉,殷延華,吳薇,嚴(yán)昆,陳敏華【摘要】目的探討超聲造影(contrastenhancedultrasound,CEUS)在經(jīng)皮肺穿刺活檢的臨床應(yīng)用價(jià)值。方法132例肺周占位的患者進(jìn)行超聲引導(dǎo)下經(jīng)皮肺穿刺活檢。其中72例患者穿刺前進(jìn)行CEUS檢查,為造影組;之前60例未進(jìn)行CEUS檢查,為
2、對(duì)照組。比較兩組超聲圖像特點(diǎn),穿刺活檢次數(shù),病理診斷準(zhǔn)確率以及并發(fā)癥等方面的差異,分析CEUS對(duì)提高經(jīng)皮肺穿刺活檢成功率的應(yīng)用價(jià)值。結(jié)果造影組肺周病灶內(nèi)部壞死的顯示率為44.4%(32/72),高于對(duì)照組的6.7%(4/60),差異有統(tǒng)計(jì)學(xué)意義(P<0.01)。在造影組中,12.5%(9/72例)顯示病灶伴局部不張肺組織,CEUS可清楚顯示位于不張肺組織內(nèi)的病灶,對(duì)照組為1.7%(1/60例),兩組差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。造影組對(duì)照病理,診斷正確率為95.8%(69/72),高于對(duì)照組的80%(48/60),差
3、異有顯著統(tǒng)計(jì)學(xué)意義(P<0.叭)。兩組穿刺次數(shù)分別為(2.4±0.6)次和(2.6±0.6)次,差異無(wú)統(tǒng)計(jì)學(xué)意義。并發(fā)癥情況比較,兩組發(fā)生率分別為2%與33%.均無(wú)嚴(yán)重并發(fā)癥,差異無(wú)統(tǒng)計(jì)學(xué)意義。結(jié)論經(jīng)皮肺穿刺前行CEUS檢查可對(duì)病灶內(nèi)部結(jié)構(gòu)進(jìn)行有效評(píng)估以及篩選適應(yīng)證,并可顯著提高病理診斷正確率,在經(jīng)皮肺穿刺活檢中具有重要指導(dǎo)價(jià)值?!娟P(guān)鍵詞】穿刺活檢;超聲造影;肺腫瘤;診斷率中圖分類(lèi)號(hào):R734.2文獻(xiàn)標(biāo)志碼:A文章編號(hào):1008—794X(2014)一06—0482—05Applicationofcontrast—enha
4、ncedultrasonographyinimprovingthesuccessrateofpercutaneousbiopsyforperipheralpulmonarylesionsWANGsong,YANGWei,ZHANGHui,YlNYan—huaWUWei,YANKun,CHENMin—hua.KeyLaboratoryofCarcinogenesisandTranslationalResearch(MinistryofEducation),DepartmentofUltrasonography,PekingU
5、niversityCancerHospital&Institute,Beijing100142.ChinaCorrespondingauthor:YANGWei,E—mail:weiwei02032001@gmail.COnl【Abstract】ObjectiveToinvestigatetheclinicalapplicationofcontrastenhanceduhrasonography(CEUS)inperformingpercutaneousbiopsyforperipherallunglesions.Meth
6、odsAtotalof132patientswithperipherallunglesionsunderwentuhrasonography—guidedpereutaneousbiopsy.Ofthe132patients,72receivedCEUSexaminationsbeforebiopsy(CEUSgroup),and60receivedsimplebiopsywithnoCEUSexamination(controlgroup).Theuhrasonographyimagingcharacteristics,
7、thetimesofpuncturebiopsy,thediagnosticaccuracyrateandtheincidenceofcomplicationswererecorded,andtheresultswerecomparedbetweenthetwogroups.TheclinicalvalueofCEUSinimprovingtheSUCCESSrateofpereutaneousbiopsyforperipheralpuhnonarylesionswasanalyzed.ResultsNecrosis(ar
8、easofecholess)wasdemonstratedin44.4%ofthepatients(32/72)inCEUSgroup,whileitwasdisplayedinonly6.7%ofthepatients(4/60)inthecontrolgroup.Thedemonstrationra