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1、醫(yī)學(xué)影像學(xué)雜志2005年第15卷第6期 JMedImagingVol.15No.62005髓母細(xì)胞瘤的MRI診斷及臨床分析122莫友發(fā),趙云輝,許乙凱(1.廣東省東莞市虎門醫(yī)院影像中心 廣東 東莞 523902;2.南方醫(yī)科大學(xué)南方醫(yī)院影像中心 廣東 廣州 510515)【摘 要】 目的:分析髓母細(xì)胞瘤的臨床特點(diǎn)、磁共振成像(MRI)征象及其診斷價(jià)值。方法:收集經(jīng)手術(shù)與病理證實(shí)的髓母細(xì)胞瘤46例,全部病例均行MRI檢查。結(jié)果:髓母細(xì)胞瘤主要臨床表現(xiàn)為頭痛、惡性、嘔吐及行走不穩(wěn)。腫瘤位于小腦蚓部42例,小腦半球4例。MRI上,病灶在T1WI為低信號(hào)者占81%(3
2、3/46),混雜信號(hào)者占19%(13/46);T2WI上為高信號(hào)者81%(33/46),混雜信號(hào)者占19%(13/46);Gd2DTPA增強(qiáng)掃描顯示病灶呈均勻強(qiáng)化者占75%(34/46),不均勻強(qiáng)化者占20%(9/46),有5%(3/46)的病灶顯示環(huán)狀強(qiáng)化,瘤周有不同程度的水腫及伴有不同程度腦積水表現(xiàn)。MRI對(duì)髓母細(xì)胞瘤檢出率、定位及定性診斷正確率分別為100%、96%、90%。結(jié)論:髓母細(xì)胞瘤的MRI表現(xiàn)具有一定特征性。MRI檢查多方位、多序列成像,對(duì)其診斷、治療及術(shù)后隨訪等有重要作用,因此髓母細(xì)胞瘤的檢查應(yīng)首選MRI。【關(guān)鍵詞】 小腦腫瘤,髓母細(xì)胞瘤;磁
3、共振成像中圖分類號(hào):R739.41;R445.2 文獻(xiàn)標(biāo)識(shí)碼:A 文章編號(hào):1006-9011(2005)06-0449-03Medulloblastoma:theroleofMRIanditsclinicalanalysisMOYou2fa,ZHAOYun2hui,XUYi2kai.RadiologicalSection,HumenHospital,Dongguan,GuangdongProvince510515,China【Abstract】Objective:Thepurposesofthisstudyweretoanalyzeclinicalc
4、haracteristicanditssignsonimagesofmagneticresonanceimaginganddiagnosisvaluesofMRI.Methods:Therewereforty2sixpatientswithmedulloblastoma.Thediagnosisofallpatientshadcon2firmedbyoperationandpathology.Inthesepatients,themalewerethirty2threeandthefemalewerethirteen.Theageofthesepatients
5、rangedfromfivetoforty2twoyearsold,meanthirteenyearsold.AllpatientshadcheckedbyMRI.Results:Themainclinicalmanifesta2tionsofmedulloblastomawereheadache,nausea,vomitandinstablewalk.Thetumorlocatedvermisofcerebelluminforty2twopatients,andlocatedcerebellarhemisphereinfourpatients.Inthese
6、patients,malechildrenweremajority.OnMRI,inforty2sixpatients,tumorswerelow2signal2intensityinthirty2threepatients(81%)andwereintermixsignalintensityinthirteenpatients(5%)onT12weightedim2ages;tumorswerehigh2signal2intensityinthirty2threepatients(81%)andwereintermixsignalintensityinthi
7、rteenpatients(5%)onT22weightedimages;afterinjectingGd2DTPA,thetumorsinthirty2fourpatientswereshowedhomogeneousenhancementandinninepatientswereheterogeneousenhancement,therewerethreepatientsthattheirtumorswereshowedcircularenhancement.Insomepatients,thetu2morswereoccurredcysticchange
8、,hemorrhage,calcifi
