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1、Lecturer:GuoXiangClassificationandDiagnosisofastrocytoma(星形細(xì)胞瘤)MorbidityofAstrocytomaAstrocytictumor78%GliomaPrimarybraintumor40%5-10100000MorbidityTypeofAstrocytomaWHOclassificationⅠ~ⅣⅠ級(jí)毛細(xì)胞型星形細(xì)胞瘤、室管膜下巨細(xì)胞星形細(xì)胞瘤Ⅱ級(jí)彌漫型星形細(xì)胞瘤Ⅲ級(jí)間變型星形細(xì)胞瘤Ⅳ級(jí)膠質(zhì)母細(xì)胞瘤PilocyticastrocytomaANDSubependy
2、malgiantcellastrocytomasDiffuseastrocytomaAnaplasticastrocytomaGlioblastomaSubependymalgiantcellastrocytomas-GradeⅠReddish-yellowpimpleschromosomaldisorder染色體疾病epiloia(結(jié)節(jié)性硬化)8Y~18Y(male-to-femaleratio=3:1)subependymalnodulescontrast-enhancehydrocephalus腦積水favorableclin
3、icaloutcome紅黃色丘疹T1T2T1-enhanceCTnon-contrastM16yPilocyticastrocytoma-GradeⅠChildrenCerebellumhemispheresorvermisSolidandcysticpartNormaltissue>solidnodule>cysticmass>CSFindensityonNCCTMRI:ahigh-signal-intensitycystsurroundingaiso-intensitymuralnoduleonT2Contrastenhance
4、mentwithbothCTandMRIvermisF62YT1T2T1-enhancePathology彌漫型星形細(xì)胞瘤屬于交界性腫瘤,容易復(fù)發(fā),且惡性度有不斷增加的趨勢(shì),最終發(fā)展為膠質(zhì)母細(xì)胞瘤。Grade-ⅡDiffuseastrocytomaGrade-ⅢAnaplasticastrocytomaGrade-ⅣGlioblastomaDiffuseastrocytoma-GradeⅡborderlinetumorsurgerymalignancywillbehigherrecurCharacteristicImagingCha
5、racteristicBrainstemorsupratentorialwhitematterpoorlydefinedborderLow-densityonCTslightly>CSFNosignificantenhancementNoorslightlyenhancementCysticchangeT1WIhypointensitysignalT2WIhyperintensitysignalF54YSurgicalfieldandSpecimenThetumorshoweddiffuselyinfiltratedgrowing.
6、NOhemorrhageandnecrosis.Anaplasticastrocytoma-GradeⅢthetumorenhanceddistinctlyT1-enhanceFLAIRT1T2T1Glioblastoma-Grade-ⅣAdulthoodMixeddensityorsignallesionHemorrhageandnecrosisContrast-enhanceBecausethetreatmentofastrocytomaismainlybasedonpathologicaltype,soitwillbevery
7、helpfultomakeanaccuratediagnosistothelevelofcells.ThankYou!ThankYouforYourAttention