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1、ReviewsF.Braetetal.DOI:10.1002/anie.200903463BiosensorsandCarbonNanomaterialsCarbonNanomaterialsinBiosensors:ShouldYouUseNanotubesorGraphene?WenrongYang,KyleR.Ratinac,SimonP.Ringer,PallThordarson,J.JustinGooding,andFilipBraet*Keywords:biosensors·carbonnanom
2、aterials·carbonnanotubes·graphene·sensorsAngewandteChemie2114www.angewandte.org2010Wiley-VCHVerlagGmbH&Co.KGaA,WeinheimAngew.Chem.Int.Ed.2010,49,2114–2138AngewandteBiosensorsChemieFromdiagnosisoflife-threateningdiseasestodetectionofbiologicalFromtheContent
3、sagentsinwarfareorterroristattacks,biosensorsarebecomingacritical1.Introduction2115partofmodernlife.Manyrecentbiosensorshaveincorporatedcarbonnanotubesassensingelements,whileagrowingbodyofworkhas2.UncommonCarbon:Anbeguntodothesamewiththeemergentnanomaterial
4、graphene,whichIntroductiontoCNTsandiseffectivelyanunrollednanotube.WiththiswidespreaduseofcarbonGraphene2116nanomaterialsinbiosensors,itistimelytoassesshowthistrendis3.RecentDevelopmentsintheUsecontributingtothescienceandapplicationsofbiosensors.ThisReviewo
5、fCNTsinBiosensors2120explorestheseissuesbypresentingthelatestadvancesinelectro-chemical,electrical,andopticalbiosensorsthatusecarbonnanotubes4.Graphene-BasedBiosensors2126andgraphene,andcriticallycomparestheperformanceofthetwocarbonallotropesinthisapplicati
6、on.Ultimately,carbonnano-5.CarbonComparisons2131materials,althoughstilltomeetkeychallengesinfabricationand6.SummaryandOutlook2133handling,haveabrightfutureasbiosensors.1.Introductionthebiosensinginterfacesothattheanalyteselectively[9,10]interactswiththebios
7、ensingsurface;achievementof[11,12]Therehasbeenanexplosionofinterestintheuseofefficienttransductionofthebiorecognitionevent;nanomaterialsforthedevelopmentofbiosensors,andcarbonincreasesinthesensitivityandselectivityofthebiosen-[1–3][13,14]nanotubes(CNTs)area
8、ttheforefrontofthisexplosion.sor;andimprovementofresponsetimesinverysensitive[15]Theinterestispartlymotivatedbytheabilitytoimprovesystems.Morespecificchallengesinclude:makingbiosen-macroscalebiosensors