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1、Triclosanisanantimicrobialcommonlyfoundinsoaps,閱讀理解答案 閱讀理解A Triclosanisanantimicrobialcommonlyfoundinsoaps,shampoos,toothpastesandmanyotherhouseholditems.Despiteitswidespreaduse,researchersatUniversityofCalifornia,SanDiegoSchoolofMedicinereportpotentiallyserious
2、consequencesoflong-termexposuretothechemical.Thestudy,publishedNov.17byProceedingsoftheNationalAcademyofSciences,showsthattriclosancausesliverfibrosisandcancerinlaboratorymicethroughmolecularmechanismsthatarealsorelevantinhumans.“Triclosan’sincreasingdetectioninen
3、vironmentalsamplesanditsincreasinglybroaduseinconsumerproductsmayovercomeitsmoderatebenefitandpresentaveryrealriskoflivertoxicityforpeople,asitdoesinmice,particularlywhencombinedwithothercompoundswithsimilaraction,”saidRobertH.Tukey,PhD,professorinthedepartmentsof
4、ChemistryandBiochemistryandPharmacology.Tukeyledthestudy,togetherwithBruceD.Hammock,PhD,professoratUniversityofCalifornia,Davis.BothTukeyandHammockaredirectorsofNationalInstituteofEnvironmentalHealthSciences(NIEHS)SuperfundProgramsattheirrespectivecampuses. Tukey
5、,Hammockandtheirteams,includingMei-FeiYueh,PhD,foundthattriclosandisruptedliverintegrityandcompromisedliverfunctioninmousemodels.Miceexposedtotriclosanforsixmonths(roughlyequivalentto18humanyears)weremoresusceptibletochemical-inducedlivertumors.Theirtumorswerealso
6、largerandmorefrequentthaninmicenotexposedtotriclosan. Thestudysuggeststriclosanmaydoitsdamagebyinterferingwiththeconstitutiveandrostanereceptor,aproteinresponsiblefordetoxifying(clearingaway)foreignchemicalsinthebody.Tocompensateforthisstress,livercellsproliferat
7、eandturnfibroticovertime.Repeatedtriclosanexposureandcontinuedliverfibrosiseventuallypromotetumorformation. canwelearnabout”triclosan” Itisgeneratedinsoaps,shampoosandmanyotherhouseholditems Ithasbeenusedinconsumerproductsforeconomiceffects Whetheritdoesharmto
8、humansstillremainsamystery Itwillcausedamageonlywhenitiscombinedwithothercompound weassumethat“constitutiveandrostanereceptor”isA,”livercells”isB,”tri
