triclosan is an antimicrobial commonly found in soaps, 閱讀理解答案

triclosan is an antimicrobial commonly found in soaps, 閱讀理解答案

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時間:2018-10-18

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1、Triclosanisanantimicrobialcommonlyfoundinsoaps,閱讀理解答案  閱讀理解A  Triclosanisanantimicrobialcommonlyfoundinsoaps,shampoos,toothpastesandmanyotherhouseholditems.Despiteitswidespreaduse,researchersatUniversityofCalifornia,SanDiegoSchoolofMedicinereportpotentiallyserious

2、consequencesoflong-termexposuretothechemical.Thestudy,publishedNov.17byProceedingsoftheNationalAcademyofSciences,showsthattriclosancausesliverfibrosisandcancerinlaboratorymicethroughmolecularmechanismsthatarealsorelevantinhumans.“Triclosan’sincreasingdetectioninen

3、vironmentalsamplesanditsincreasinglybroaduseinconsumerproductsmayovercomeitsmoderatebenefitandpresentaveryrealriskoflivertoxicityforpeople,asitdoesinmice,particularlywhencombinedwithothercompoundswithsimilaraction,”saidRobertH.Tukey,PhD,professorinthedepartmentsof

4、ChemistryandBiochemistryandPharmacology.Tukeyledthestudy,togetherwithBruceD.Hammock,PhD,professoratUniversityofCalifornia,Davis.BothTukeyandHammockaredirectorsofNationalInstituteofEnvironmentalHealthSciences(NIEHS)SuperfundProgramsattheirrespectivecampuses.  Tukey

5、,Hammockandtheirteams,includingMei-FeiYueh,PhD,foundthattriclosandisruptedliverintegrityandcompromisedliverfunctioninmousemodels.Miceexposedtotriclosanforsixmonths(roughlyequivalentto18humanyears)weremoresusceptibletochemical-inducedlivertumors.Theirtumorswerealso

6、largerandmorefrequentthaninmicenotexposedtotriclosan.  Thestudysuggeststriclosanmaydoitsdamagebyinterferingwiththeconstitutiveandrostanereceptor,aproteinresponsiblefordetoxifying(clearingaway)foreignchemicalsinthebody.Tocompensateforthisstress,livercellsproliferat

7、eandturnfibroticovertime.Repeatedtriclosanexposureandcontinuedliverfibrosiseventuallypromotetumorformation.  canwelearnabout”triclosan”  Itisgeneratedinsoaps,shampoosandmanyotherhouseholditems  Ithasbeenusedinconsumerproductsforeconomiceffects  Whetheritdoesharmto

8、humansstillremainsamystery  Itwillcausedamageonlywhenitiscombinedwithothercompound  weassumethat“constitutiveandrostanereceptor”isA,”livercells”isB,”tri

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