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1、第14卷第7期遼寧中醫(yī)藥大學(xué)學(xué)報Vol.14No.72012年7月JOURNALOFLIAONINGUNIVERSITYOFTCMJul.,2012急性冠脈綜合征痰瘀因素與冠脈病變程度相關(guān)性研究于開鋒,楊關(guān)林,張會永,張哲,陳韋,趙佳欣(遼寧中醫(yī)藥大學(xué),遼寧沈陽110847)摘要:目的:探索急性冠脈綜合征痰瘀因素與冠脈病變程度相關(guān)性。方法:以診斷為ACS且行CAG術(shù)證實(shí)冠脈至少一支狹窄≥50%的125例患者為例,采集術(shù)后24h內(nèi)四診資料等臨床相關(guān)數(shù)據(jù),并進(jìn)行中醫(yī)辨證分型,對數(shù)據(jù)進(jìn)行“相關(guān)性”分析。結(jié)果
2、:①痰瘀互結(jié)證與非痰瘀互結(jié)證,在病變累及支數(shù)上未體現(xiàn)明顯統(tǒng)計學(xué)差異(P=0.104)。②血瘀證與非血瘀證,在病變狹窄程度上有顯著的統(tǒng)計學(xué)差異(P=0.000)。③痰濁證與非痰濁證,在病變支數(shù)上體現(xiàn)一定的統(tǒng)計學(xué)差異(P=0.053)。④血瘀證與Gensini積分存在一定線性相關(guān)(r=-0.249),且血瘀證組積分明顯高于非血瘀證組。結(jié)論:冠心病急性冠脈綜合征痰瘀因素與冠脈病變程度存在相關(guān)性。關(guān)鍵詞:急性冠脈綜合征;痰血瘀阻證;冠狀動脈病變程度;相關(guān)研究中圖分類號:R543.3文獻(xiàn)標(biāo)識碼:A文章編號:16
3、73-842X(2012)07-0154-03RelationshipbetweenPhlegmandBloodStasisElementsofAcuteCoronarySyndromesandtheExtentofCoronaryArteryLesionsYUKai-feng,YANGGuan-lin,ZHANGHui-yong,ZHANGZhe,CHENWei,ZHAOJia-xin(LiaoningUniversityofTraditionalChineseMedicine,Shenyang11
4、0847,Liaoning,China)Abstract:Objective:Tostudytherelationshipbetweenthephlegmandbloodstasiselementsofacutecoronarysyndromesandtheextentofcoronaryarterylesions.Method:Taking125caseswhowerediagnosedasacutecoronarysyndromesandconfirmedatleastoneofthecorona
5、rystenosiswasmorethan50%inourheartdiseasemedicinewardforinstance,tocollectthepatients'fourdiagnosticinformationaftercoronaryarteriographywithin24handdifferentiatethetypesofsyndromeofTCM,thentoanalyzetherelationshipbetweenthephlegmandbloodstasiselementsa
6、ndtheextentofcoronaryarterylesions.Results:①Thesyndromeofphlegmandbloodstasiswasnotstatisticallydifferentwiththethesyndromeofnon-phlegmandbloodstasisonlesionscount(P=0.104).②Thesyndromeofbloodstasiswasstatisticallydifferentwiththesyndromeofnon-bloodstas
7、isonlesionsnarrowobviously(P=0.000).③Thesyndromeofphlegmwasnotstatisticallydifferentwiththesyndromeofnon-phlegmonlesionscount(P=0.053).④Thesyndromeofbloodstasiswaslinearrelatedwithgensiniscore(r=-0.249),andthegensiniscoreofthesyndromeofbloodstasiswassig
8、nificantlyhigherthanthatofthesyndromeofnon-bloodstasis.Conclusion:Thereisacorrelationbetweenthephlegmandbloodstasiselementsandtheextentofcoronaryarterylesions.Keywords:ACS;thesyndromeofphlegmandbloodstasis;theextentofcoronaryarte