陰性淋巴結(jié)數(shù)目對胃癌手術(shù)患者預(yù)后的影響.pdf

《陰性淋巴結(jié)數(shù)目對胃癌手術(shù)患者預(yù)后的影響.pdf》由會(huì)員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在工程資料-天天文庫。

1、·3632·現(xiàn)代預(yù)防醫(yī)學(xué)2014年第41卷第19期ModemPreventiveMedicine，2014，Vo1．41，NO．19·臨床與預(yù)防·陰性淋巴結(jié)數(shù)目對胃癌手術(shù)患者預(yù)后的影響易偉，錢洪軍，陳帆解放軍第九四醫(yī)院普外科，江西南昌330002摘要：目的探討陰性淋巴結(jié)數(shù)目對胃癌手術(shù)患者預(yù)后的影響。方法回顧性分析2006年1月一2009年9月有完整隨訪資料的203例胃癌手術(shù)患者的臨床資料，分別對影響腫瘤復(fù)發(fā)及術(shù)后生存時(shí)間的預(yù)后因素進(jìn)行單因素及多因素分析。結(jié)果203例胃癌手術(shù)患者的總體復(fù)發(fā)率為34．98％，總體3年生存率為71．92％。單因素分析顯示更少的陰性淋巴結(jié)數(shù)目(<10枚)是影

2、響胃癌患者術(shù)后復(fù)發(fā)及生存時(shí)間的顯著危險(xiǎn)因素(P

3、impactofthenumberofnegativelymphnodesingastriccancerpatientsaftercurativegastrectomyYIWei，QIANHong~Ha，CHENFanDepartmentofGeneralSurgery,the94MilitaryHospitaloftheChinesePeopleLiberationArmy,Nanchang,Jiangxi330002，ChinaAbstract：ObjectiveToinvestigatetheprognosticimpactofthenumberofnegativelymphn

4、odesingastriccanceraftercurativegastreetomy．MethodsThisstudyinvolved203patientswithgastriccancer，whounderwentcurativegastrectomywithcompletefollow-updatafromJanuary2006toSeptember2009．Factorswhichinfluencedtumorrecurrenceandoverallsurvivaltimewereevaluatedbyunivariateandmultivariateanalysis．Res

5、ultsTherecurrencerateof203patientswithgastriccancerwas34．98％，andthe3-yearoveralsurvivalratewas71．92％．Onunivariateanalysis，thefewernegativelymphnodes(<10)hadastatisticallysignificantnegativeimpactontumorrecurenceandoverallsurvivaltime(尸0．01)．Multivariateanalysisshowedthattumorsize，tumordiferenti

6、ation，depthofinvasion，thenumberofpositivelymphnodes，andthenumberofnegativelymphnodeswereindependentpredictorsoftumorrecurrenceandoverallsurvivaltime．Stratifiedanalysisrevealedthatthefewernegativelymphnodes(<1o)hadastatisticallysignificantnegativeimpactonoverallsurvivaltime(尸≮0．01)ingastriccance

7、rpatientswithstageIII．ConclusionInsuficientnumberofnegativelymphnodesisanindependentriskfactoraffectingtheprognosisofpatientswithgastriccancerundergoingcurativegastrectomy．Morelymphnodesshouldbereseetedtoinsuresuficientnumberofneg