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《布托啡諾超前鎮(zhèn)痛對(duì)羅哌卡因臂叢阻滯效果影響的臨床評(píng)》由會(huì)員上傳分享,免費(fèi)在線閱讀,更多相關(guān)內(nèi)容在行業(yè)資料-天天文庫。
1、布托啡諾超前鎮(zhèn)痛對(duì)羅哌卡因臂叢阻滯效果影響的臨床評(píng)價(jià)王德明張?jiān)艑O永興何旭[作者單位:266071山東省青島市,解放軍第401醫(yī)院全軍手外科中心麻醉科(王德明、張?jiān)?、何旭);首都醫(yī)科大學(xué)附屬北京同仁醫(yī)院麻醉科(孫永興))摘要]目的評(píng)價(jià)布托啡諾超前鎮(zhèn)痛對(duì)羅哌卡因臂叢阻滯效果的影響。方法選擇80例擬行前臂與手部手術(shù)的成年男性患者,ASAⅠ-Ⅱ級(jí)。隨機(jī)分為四組(n=20),每組均用4mg/ml羅哌卡因40ml作腋路臂叢神經(jīng)阻滯,各組局麻藥均不加腎上腺素。A組:對(duì)照組,臂叢神經(jīng)阻滯前5min靜注安慰劑。B組、C組、D組分別在臂
2、叢神經(jīng)阻滯前5min靜注布托啡諾0.5mg、1mg、2mg。在麻醉后5、10、15、20、30、45、60min對(duì)麻醉質(zhì)量進(jìn)行評(píng)價(jià),記錄麻醉起效時(shí)間、麻醉維持時(shí)間、手術(shù)時(shí)間、圍術(shù)期各時(shí)間點(diǎn)的疼痛評(píng)分,疼痛程度采用“視覺模擬評(píng)分法”(VAS)評(píng)定、不良反應(yīng)發(fā)生率。結(jié)果麻醉維持時(shí)間A組略短于B組,但兩組比較差異無顯著性(P>0.05);C組、D組明顯長于A組、B組(P<0.01)。術(shù)后8h、12h、24h時(shí)疼痛評(píng)分(VAS),A組、B組高于C組、D組(P<0.01)。C組、D組輔助用藥量明顯低于A組和B組。結(jié)論布托啡諾超前鎮(zhèn)
3、痛效果確切,能夠增強(qiáng)羅哌卡因臂叢神經(jīng)阻滯效果,延長術(shù)后鎮(zhèn)痛時(shí)間,不良反應(yīng)發(fā)生率低,值得臨床采用。[關(guān)鍵詞]:布托啡諾;超前鎮(zhèn)痛;臂叢神經(jīng)阻滯;羅哌卡因布托啡諾超前鎮(zhèn)痛對(duì)羅哌卡因臂叢麻醉效果影響的臨床評(píng)價(jià)EffectsofbutorphanolpreempitiveanalgesiaonbrachialplexusblockwithropivacaineWANGDe-ming,ZHANGYuan-xin,SUNYong-xing,etal.Departmentofanaesthesia,theCenterofHandSur
4、gery,401sthospitalofthePLA,Qingdao266071,China[Abstract]ObjectiveToevaluatetheclinicaleffectsofbutorphanolpreempitiveanalgesiaonbrachialplexusblockwithropivacaine.MethodsEightyadultmalepatients(ASAⅠ-Ⅱ)undergoingforearmorhandsurgeryweredividedrandomlyintofourgroup
5、s.Everygroupreceived4mg/mlropivacaine40mlinaxillaryapproachbrachialplexusblock.GroupA(controlgroup)intravenousinjectedthepatientwithplacebobefore5minbrachialplexusblock.GroupB、groupCandgroupD(testgroup)respectivelyintravenousinjectedthepatientwithbutorphanol0.5mg
6、、1mgand2mgbefore5minbrachialplexusblock.Allblokswereperformedbythesameanaesthetist.Thedegreeofnerveblockadewasevaluatedat5,10,15,20,30,40and60minafterlocalanesthticinfusion.Theonsettimeofbothfeelingandmotorblock;thedurationtimeofnerveblockade;intra-andpostoperati
7、veVAS(thevisualanaloguescale)scores,complicationsandsideeffectswererecorded.ResultsThedurationofnerveblockadeingroupBwaslongerthanthatingroupA(P>0.05),ThedurationofnerveblockadeingroupCandDwasobviouslongerthanthatingroupAandB(P<0.01).Atthesametime,thescoresofVASa
8、tpostoperative8h、12h、24hingroupAandBwashigherthanthatingroupCandD(P<0.01).ThedosageofadjuvantingroupCandDwaslessthanthatingroupAandB.ConclusionTheeffectofbutor