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1、Anxietydisorders,Obsessive-CompulsiveandRelateddisorders,andTraumaandStressor-relatedDisordersHeidiCombs,MDAssistantProfessorUniversityofWashington/HMCPaulZarkowskiAssistantProfessorAFacultyDisclosureIhavenofinancialrelationshipstodiscloserelatingtothesubjectmatterofthispresenta
2、tionWhatwewillreviewEpidemiologyofanxietyandrelateddisordersComorbidpsychiatricdiagnosesDiagnosticcriteriaforanxietyandrelateddisordersNeuroimagingfindingsofanxietydisordersQuickquestionstoscreenforanxietydisordersTreatmentincludingpsychotherapyandpsychopharmacologyObjectivesLis
3、ttheprevalenceofanxietyandrelateddisordersIdentifycomorbidpsychiatricdiagnosesPerformaquickscreenforanxietyandrelateddisordersApplygeneralpharmacologicapproachestothetreatmentofanxietydisordersGeneralconsiderationsforanxietydisordersOftenhaveanearlyonset-teensorearlytwentiesShow
4、2:1femalepredominanceHaveawaxingandwaningcourseoverlifetimeSimilartomajordepressionandchronicdiseasessuchasdiabetesinfunctionalimpairmentanddecreasedqualityoflifeNormalversusPathologicAnxietyNormalanxietyisadaptive.Itisaninbornresponsetothreatortotheabsenceofpeopleorobjectsthats
5、ignifysafetycanresultincognitive(worry)andsomatic(racingheart,sweating,shaking,freezing,etc.)symptoms.Pathologicanxietyisanxietythatisexcessive,impairsfunction.FocusedNeuroanatomyReviewAmygdala-involvedwithprocessingofemotionallysalientstimuliMedialprefrontalcortex(includesthean
6、teriorcingulatecortex,thesubcallosalcortexandthemedialfrontalgyrus)-involvedinmodulationofaffectHippocampus-involvedinmemoryencodingandretrievalThedifferentialdiagnosisofanxiety.PsychiatricandMedicaldisorders.PsychiatrClinNorthAm1985Mar;8(1):3-23PrimaryversusSecondaryAnxietyAnxi
7、etymaybeduetooneoftheprimaryanxietydisordersORsecondarytosubstanceabuse(Substance-InducedAnxietyDisorder),amedicalcondition(AnxietyDisorderDuetoaGeneralMedicalCondition),anotherpsychiatriccondition,orpsychosocialstressors(AdjustmentDisorderwithAnxiety)AnxietydisordersSpecificpho
8、biaSocialanxietydisorder(SAD)Panicdisorder(PD)A
