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1、軀體化障礙患者神經(jīng)認(rèn)知功能比較【摘要】目的:探討軀體化障礙患者神經(jīng)認(rèn)知功能障礙的特點(diǎn)。方法:對(duì)60例符合ICD-10軀體化障礙診斷標(biāo)準(zhǔn)的患者給予藥物治療8周,在治療前、后給予威斯康星卡片分類測(cè)驗(yàn)(WCST)、持續(xù)操作測(cè)驗(yàn)(CPT),同時(shí)測(cè)驗(yàn)50例正常人作為對(duì)照組?;颊呓M的測(cè)驗(yàn)結(jié)果進(jìn)行自身前后比較、并分別與正常對(duì)照組進(jìn)行組間比較。結(jié)果:患者組治療前、后WCST的總應(yīng)答數(shù)、完成分類數(shù)、持續(xù)性錯(cuò)誤數(shù)、非持續(xù)性錯(cuò)誤數(shù)自身比較,差異有統(tǒng)計(jì)學(xué)意義(P<0.05~0.01)。患者組治療前WCST的總應(yīng)答數(shù)、完成分類
2、數(shù)、持續(xù)性錯(cuò)誤數(shù)、非持續(xù)性錯(cuò)誤數(shù)與正常對(duì)照組組間比較,差異有統(tǒng)計(jì)學(xué)意義(P<0.01~0.001),治療后與正常對(duì)照組組間比較,差異無統(tǒng)計(jì)學(xué)意義(P>0.05)?;颊呓M治療前、后CPT得分比較,在無干擾時(shí)差異無統(tǒng)計(jì)學(xué)意義(P>0.05),有干擾時(shí)差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。患者組治療前CPT得分與正常對(duì)照組組間比較,在無干擾時(shí)差異無統(tǒng)計(jì)學(xué)意義(P>0.05),有干擾時(shí)差異有統(tǒng)計(jì)學(xué)意義(P<0.05),治療后與正常對(duì)照組比較,差異無統(tǒng)計(jì)學(xué)意義(P>0.05)。結(jié)論:軀體化障礙患者存在神經(jīng)認(rèn)知功能障
3、礙,但經(jīng)過治療可以改善。【關(guān)鍵詞】軀體化障礙;神經(jīng)認(rèn)知功能;威斯康星卡片分類測(cè)驗(yàn);持續(xù)操作測(cè)驗(yàn)Comparisonofneurocognitivefunctioninpatientswithsomatizationdisorder〔Abstract〕Objective:Toexploretheneurocognitivefunctioninpatientswithsomatizationdisorder.Methods:sixtysomatizationdisorderpatientswhometth
4、eICD-10weretreatedfor8weeks,theyweremeasuredwithWisconsinCardSortingTest(WCST)andContinuousperformanceTest(CPT)beforeandaftertherapy.AndfiftyhealthypeoplesweremeasuredwithWCSTandCPTascontrolgroup.Thetestresultsofpatientsgroupwerecomparedbeforeandafterth
5、erapy,andtheywerecomparedwiththecontrolgrouprespectively.Results:Thesignificantdifferenceinthetotaltrials,numberofcompletedclassification,preservativeerrors,nor-preservativeerrorsofWCSTwereobservedbetweembeforeandaftertherapyofpatientsgroup(P<0.05~0.01)
6、.Andthesameresultswasalsofoundbetweenpatientsgroupbefortherapyandcontrolgroup(p<0.05).Andnosignificantdifferencewasalsofoundbetweenpatientsgroupaftertherapyandcontrolgroup(p>0.05).ComparedtheCPTscoresbetweenpatientsgroupofbeforeandaftertherapy,thesignif
7、icantdifferencewasn’tfoundinnointerferestimulus(P>0.05),buttheycouldbefoundininterferestimulus(P<0.05).Andthesameresultsalsobefoundbetweenpatientsgroupofbeforetherapyandcontrolgroup.Butnosignificantdifferencebetweenpatientsgroupofaftertherapyandcontrolg
8、roup(P>0.05).Conclusion:locatedintheTomb,DongShenJiabang,deferthenextdayfocusedontheassassination.Linping,Zhejiang,1ofwhichliquorwinemasters(WuzhensaidinformationisCarpenter),whogotAfewbayonets,duetomissedfatal,whennightcame5Pati