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1、CT在難治性癲癇治療中的綜合應(yīng)用［摘要］目的探討CT在難治性癲癇治療中的應(yīng)用。方法將1189例癲癇患者均應(yīng)用常規(guī)的抗癲癇藥物系統(tǒng)治療6個月，將其中符合難治性癲癇診斷的160例，從中隨機(jī)選取80例患者全部進(jìn)行CT螺旋掃描，依據(jù)CT掃描結(jié)果，將CT陽性結(jié)果的患者分為A組，陰性患者分為B組，其余80例患者作為C組。A、B兩組患者除繼續(xù)應(yīng)用常規(guī)一線抗癲癇藥物治療外，均聯(lián)合應(yīng)用其他不同的治療方法，其中A組患者輔助低頻重復(fù)經(jīng)顱刺激和維生素E治療，B組患者則加服中藥及維生素E治療，C組繼續(xù)應(yīng)用常規(guī)一線抗癲癇藥物治療。12個月后再對三組患者的療
2、效進(jìn)行評估。結(jié)果A、B兩組患者經(jīng)過12個月的聯(lián)合治療，A組的有效率為74.6%，B組的有效率80.0%，與聯(lián)合治療前療效有較明顯的提高。C組的有效率為40.0%。結(jié)論CT在探討難治性癲癇的病因中有著重要作用，對其治療方案的制定起著重要的指導(dǎo)作用。［關(guān)鍵詞］CT;難治性癲癇；抗癇藥治療；中藥治療；低頻重復(fù)經(jīng)顱刺激［中圖分類號］R742.1［文獻(xiàn)標(biāo)識碼］B［文章編號］1673-9701(2015)25-0059-03ComprehensiveapplicationofCTintreatmentofrefractoryepilepsy
3、PANBinghuaWANGAiwuLENGXiaobingLIYumeiXIEXinyuanWANGXiangYichunThirdPeople’sHospital,Yichun336000，China[Abstract]ObjectiveToevaluatetheapplicationvalueofCTinthetreatmentofrefractoryepilepsy.Methods1189patientswithepilepsyweregivenconventionalantiepilepticdrugsystemati
4、ctreatmentfor6months.Amongthem，160patientsmettherefractoryepilepsydiagnosis,ofwhich80patientswererandomlyselectedtoreceiveCTspiralscanning,andbasedontheCTscanningresults,thepatientswithpositiveCTresultswereassignedtogroupAandthosewithnegativeCTresultswereassignedtogr
5、oupB,andtherest80patientswereassignedtogroupC.Inadditiontothecontinuousapplicationofconventionalfirst-lineantiepilepticdrugs,bothgroupAandgroupBweregiventhecombinedapplicationofotherdifferenttreatmentmethods.GroupAwasassistedwithlowfrequencyrepetitivetranscranialstim
6、ulationandvitaminEtreatment；groupBwasgivenadditionaloraladministrationoftraditionalChinesemedicineandvitaminEtreatment；groupCwasgiventhecontinuousapplicationofconventionalfirst-lineantiepilepticdrugs.Twelvemonthslater,efficacyofthethreegroupswasevaluated.ResultsAfter
7、12monthsofcombinedtreatment,theeffectiverateofgroupAwas74.6%andthatofgroupBwas80.0%,andtheefficacyofbothgroupsimprovedsignificantlycomparedtothatbeforethecombinationtreatment.TheeffectiverateofgroupCwas40.0%.ConclusionCTplaysanimportantroleinascertainingthepathogenes
8、isofrefractoryepilepsyandhasimportantguidingeffectonthedevelopmentoftreatmentprograms.[Keywords]CT；Refractoryepilepsy；Antiepileptic
