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1、刷檢與活檢在氣管鏡基礎(chǔ)操作中應(yīng)用順序研宄江浩陳石東南大學附屬第二醫(yī)院急診科南京中醫(yī)藥大學附屬江蘇省中臺院呼吸科摘要:目的優(yōu)化基本氣管鏡操作技術(shù)對于肺癌診斷非常重要,本研宄評估了在支氣管肺癌診斷中,經(jīng)支氣管鏡活檢和刷檢的順序,哪一個可以獲得更高的診斷率。方法我們對支氣管內(nèi)可見的98例肺癌患者隨機分為兩組:一組先活檢再刷檢,一組先刷檢再活檢。并對兩組不同順序操作的診斷率進行了比較,并對兩組腫瘤的病理和鏡下表現(xiàn)也進行了比較。只有通過支氣管鏡下基本操作后得到組織學、細胞學確診的患者冰能入組。并排除了外壓性改變沒有管腔內(nèi)表現(xiàn)、肺轉(zhuǎn)移性腫瘤、不常見的肺癌類型。結(jié)果發(fā)現(xiàn)先
2、刷檢在活檢組的診斷率比先活檢再刷檢的患者診斷率明顯提高(78.4%,40/51VS38.3%,18/47)(P<0.05)。原因可能與先活檢后黏膜出血影響刷檢結(jié)果有關(guān)。結(jié)論支氣管刷檢作為支氣管鏡檢查的基本手段在臨床運用中十分重要,本研宂中,先刷檢再活檢優(yōu)于先活檢再刷檢的基本操作,得到臨床推廣。關(guān)鍵詞:氣管鏡;活檢;刷檢;肺癌;基本氣管鏡技術(shù);收稿日期:2017-03-10AfurtherdiscussiononbrushingandbiopsyorderinthebasictechniquesofbronchoscopyIANGHaoCHENShiDepar
3、tmentofEmergencyMedicine,theSecondAffiliatedHospitalofSoutheastUniversity;Abstract:ObjectiveTodiscussbrushingandbiopsyorderinthebasictechniquesofbronchoscopy.MethodsAtotalof98patientswithvisibleendobronchialtumorswereprospectivelyandrandomlyenrolledintwogroups:thepre-biopsybrushing
4、groupreceivingtwicebrushingbeforebiopsy,andthepost-biopsybrushinggroup,onlyreceivingtwicebrushingafterbiopsy.Diagnosticyieldofbrushingwascomparedbeforeandafterbiopsy,andaswellasfordifferenttumorpathologiesandbronchoscopicmorphologies.Onlypatientswithadefinitivecytologicalorhistolog
5、icaldiagnosisoflungcancerbasedonbronchoscopytechniqueswereincluded.Patientswereexcludediftheyhadsubmucosallesions,extrinsiccompressions,pulmonarymetastasisofextrapulmonarymalignanciesoruncommonnon-smallcelllungcarcinoma(NSCLC).ResultsThediagnosticyieldforpre-biopsybrushing(78.4%,40
6、/51)wassignificantlyhigherthanpost-biopsybrushingwithinthesamepre-biopsybrushinggroup(38.3%,18/47)(P<0.05).Thereasonmightberelatedtotheeffectofmucosalbleedingcausedbybronchoscopybiopsy.ConclusionSupplementingbronchoscopicforcepsbiopsywithbrushingimprovesdiagnosticyieldinlungcancer.
7、Inourcases,pre-biopsybrushingappearstobesuperiortopost-biopsybrushinganditworthclinicalpromotion.Keyword:bronchoscopy;biopsy;brushing;lungcancer;basicbronchoscopytechniques;Received:2017-03-10肺癌是世界癌癥相關(guān)死亡的主要原因,是目前最常見的惡性腫瘤之一。其發(fā)病率在多數(shù)國家有明顯增高趨勢m。盡管診斷分期和治療不斷的改進,肺癌的5年生存率仍然低(io-2o%),預(yù)后差,且許
8、多患者確診即晚期m。因此篩選和檢測早期肺癌對提高生存