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1、匹多莫德治療小兒反復(fù)下呼吸道感染療效觀察及免疫功能變化侯芳1李戈2李蘭21.四川省第四人民醫(yī)院四川成都610016;2.四川省醫(yī)學(xué)科學(xué)院.四川省人民醫(yī)院四川成都610072【摘要】目的研究觀察匹多莫德治療小兒反復(fù)K呼吸道感染的治療效果及對(duì)患兒自身免疫功能的影響.方法選取我院2013年8月?2014年8月收治的反復(fù)下呼吸道感染患兒74例隨機(jī)分為對(duì)照組和觀察組.對(duì)照組采用止咳化痰、抗菌消炎等常規(guī)方法治療,觀察組在對(duì)照組的基礎(chǔ)上給予匹多莫德門服治療.治療后6個(gè)月內(nèi),對(duì)比兩組患者治療前沿免疫功能(IgM、IgG、IgA)水平及治療效果.結(jié)果治療前兩組患兒免疫功能比較差異不具有統(tǒng)
2、計(jì)學(xué)意義(p〉0??05);治療后,觀察組免疫功能檢測(cè)情況明顯優(yōu)于對(duì)照組,各項(xiàng)指標(biāo)比較差異均具有統(tǒng)計(jì)學(xué)意義(p<0??05>;觀察組治療有效率(91??9%)明顯高于對(duì)照組(73??0%),數(shù)據(jù)比較差異具有統(tǒng)計(jì)學(xué)意義(p<0??05).結(jié)論匹多莫德對(duì)于小兒反復(fù)下呼吸道感染具有顯著療效,安全性高,可有效提高患兒免疫功能,利于患兒成長(zhǎng)發(fā)育.【關(guān)鍵詞】小兒;下呼吸道感染;匹多莫德;免疫功能Pidotimodchildrenwithrecurrentlowerrespiratorytractinfectionobserveandimmunefunction【Abstract】O
3、bjectiveStudywaspidotimodchildrenwithrecurrentlowerrespiratorytractinfectiontherapeuticeffectsandtheimpactonchildren7sownimmunefunction??MethodUnderourhospitalinAugust2013—August2014weretreated74casesofchildrenwithrecurrentrespiratorytractinfectionwererandomlydiGvidedintocontrolgroupando
4、bservationgroup??ThecontrolgroupusingconventionalMethodsrefreshment,antibacterialanti—inflammatorytreatment,observaGtiongrouppidotimodoraltreatmentonthebasisofthecontrolgroup??Withinsixmonthsaftertreatment,immunefunction(lgMJgG,lgA)levelsandtherapeuGticeffectscomparedtwogroupsofpatientsb
5、eforeandaftertreatment??ResultTreatmentdifferencesbetweenthetwogroupsofchildrenwithimmunefunctionbeGforewasnotstatisticallysignificant(p>0??05);aftertreatment,theobservationgroupofimmunefunctiontestswerebetterthanthecontrolgroup,theindicaGtorsdifferenceswerestatisticallysignificant(p<0??
6、05);treatmentefficiencyoftheobservationgroup(91??9%)wassignificantlyhigher(73??0%),thedataandthedifferencewasstatisticallysignificant(p<0??05)??ConclusionPidotimodforchildrenwithrecurrentlowerrespiratorytractinfectionshaveasignificanteffect,safety【K'ecyhilwdorrednsc】animproveimmunefuncti
7、on,isconducivetogrowthanddevelopmentinchildren??Children;Lowerrespiratorytractinfections;Pidotimod;lmmunefunction【中圖分類號(hào)】R725.6【文獻(xiàn)標(biāo)識(shí)碼】B【文章編號(hào)】1008—6315(2015)12—0920—01連續(xù)-年內(nèi)頻繁發(fā)生呼吸道感染,明顯超出正常范圍,稱為反復(fù)呼吸道感染,其多見(jiàn)于1歲以上嬰幼兒,發(fā)病率18%左右,是兒科常見(jiàn)疾病,主要由于患兒自身免疫力不足、缺乏人體所需的的各種微量元素而致病[1?2].反復(fù)呼吸道感染