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《欖香烯乳劑聯(lián)合放療對(duì)非小細(xì)胞肺癌腦轉(zhuǎn)移治療作用的臨床研究》由會(huì)員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在學(xué)術(shù)論文-天天文庫。
1、欖香烯乳劑聯(lián)合放療對(duì)非小細(xì)胞肺癌腦轉(zhuǎn)移治療作用的臨床研宄遲洪亮山東省膠州市人民醫(yī)院腫瘤科山東膠州266300作者簡介:遲洪亮(1963—男,副主任醫(yī)師，主要從事惡性腫瘤的化療及屮醫(yī)屮藥研究.【摘要】A的探討欖香烯乳劑聯(lián)合放療治療非小細(xì)胞肺癌腦轉(zhuǎn)移的療效及安全性.方法60例非小細(xì)胞肺癌腦轉(zhuǎn)移患者隨機(jī)分為欖香烯乳聯(lián)合放療組30例(治療組)和單純放療治療組30例(對(duì)照組)，比較兩組的有效率、生活質(zhì)量及不良反應(yīng).結(jié)果治療組有效率為63.3°%,對(duì)照組有效率為40°%,兩組差異有統(tǒng)計(jì)學(xué)意義(P<0.05);治療組卡氏評(píng)分提高率為53.3%,對(duì)照組為26.7%,兩組差異有統(tǒng)計(jì)學(xué)意義(P<0.05)
2、;治療組骨髓抑制低于對(duì)照組.結(jié)論攬香烯乳劑聯(lián)合放療治療非小細(xì)胞肺癌腦轉(zhuǎn)移效果優(yōu)于單純放射治療，可提高患者的生活質(zhì)量，減少不良反應(yīng).【關(guān)鍵詞】欖香烯乳劑；放射治療；非小細(xì)胞肺癌；腦轉(zhuǎn)移ClinicalStudyofElemeneEmulsionCombinedwithRadiotherapyintheTreatmentofNon—smallCellLungCancerwithBrainMetastasisPatientsChiHongliang(Departmentofoncology,PeoplezsHospitalofJiaozhoucityinShandongProvinceJia
3、ozhou266300)[Abstract]objectiveToexploretheefficacyofelemeneemulsioncombinedwithradiotherapyintreatmentofnon—smallcelllungcancerwithbrainmetastasispatients.MethodsSixtynon—smallcelllungcancerwithbrainmetastasisweredividedintoelemeneemulsioncombinedwithradiotherapygroup(30cases)andraGdiotherapygr
4、oup(30cases)-Theefficiencyoftreatment,thequalityoflifeandadversereactionswerecomparedbetweentwogroups.ResuItTheefficacyinthetreatmentgroupwas63.3%and40%inthecontrolgroup,Therewasasignificantdifferencebetweenthetwogroupsintermsoftheirtreatmentresponse(P<0.05).andtheKPSinthetreatmentgroupwas53.3%a
5、nd26.7%inthecontrolgroupjherewasasignificantdifferencebetweenthetwogroupsintermsofthequaliGtyoflife(P<0.05).andthecasesofbonemarrowsuppressioninthetreatmentgroupwerelessthanthatinthecontrolgroup.ConclusionTheeffectofelemeneeGmulsioncombinedwithradiotherapyfornon—smallcelllungcancerwithbrainmetas
6、tasispatientsissuperiortoradiotherapy,whichcanimprovethequalityoflifeandle[skseeynwsoraddsv]ersereactions.Elemeneemulsion;Radiotherapy;Non—smallcelllungcancer;Brainmetastasis【中圖分類號(hào)】R148【文獻(xiàn)標(biāo)識(shí)碼】B【文章編號(hào)】1008—6315(2015)12—1412—01肺癌是嚴(yán)重威脅人類健康的惡性腫瘤，其發(fā)病率正逐年快速上升，嚴(yán)重危害人類的生命和健康[1].非小細(xì)胞肺癌(non—smalllungcancer,
7、NSCLC)約占肺癌發(fā)病率的80%,其中接近70%的NSCLC患者在確診吋己屬晚期,常有局部擴(kuò)散和遠(yuǎn)處轉(zhuǎn)移，難以進(jìn)行手術(shù)治療和單純性的局部治療[2].肺癌具奮較高的腦轉(zhuǎn)移率，腦轉(zhuǎn)移預(yù)后極差，中位生存期較短,嚴(yán)重影響了患者的生活質(zhì)量.近年來,隨著對(duì)中醫(yī)中藥研宄的不斷深入,欖香烯的抗腫瘤作用越來越受到相關(guān)學(xué)者的關(guān)注.本研宄觀察了欖香烯乳劑聯(lián)合放療對(duì)非小細(xì)胞肺癌腦轉(zhuǎn)移的治療效果和不良反應(yīng)，現(xiàn)報(bào)道如下.1資料與方法1.1一般資料研究對(duì)象均為我院腫瘤科2
