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1、復方抗感顆粒制備工藝學和辨證治療風熱型感冒臨床應用探究（山東省萊蕪市人民醫(yī)院山東萊蕪271100）作者簡介：陳艷紅，女，大學本科，主管藥師，現(xiàn)在山東省萊蕪市人民醫(yī)院工作。摘要：目的探討復方抗感顆粒的制備工藝學及辨證治療風熱型感冒的臨床應用。方法利用先進的生產(chǎn)工藝設備，對復方抗感顆粒的制備、工藝流程及質(zhì)量控制進行研究，同時選擇2011.03?2012.03間來我院就診的感冒患者150例，均系我院門診病人。按隨機同期分組之原則，分屬顆粒劑組與傳統(tǒng)湯劑組各75例。傳統(tǒng)湯劑及顆粒劑均采用同批號、同產(chǎn)地市售藥材，根據(jù)各自的加工工藝分別制作而成。傳統(tǒng)湯劑均根據(jù)處方原配伍劑量稱取，并按常規(guī)煎藥規(guī)程煎制，
2、每日口服2次。顆粒劑則取傳統(tǒng)湯劑日量生藥，按其加工工藝制備成2袋成藥，每袋10克。每次一袋，日服2次。服用時僅需將成品沸水提泡3?5min,略加攪拌便可服用。結(jié)果經(jīng)用上述方法治療后，顆粒劑組患者痊愈67例，取得痊愈率為89.33%,顯效6例，有效2例,取得總有效率為100.00%；湯劑組患者痊愈49例，取得痊愈率為65.33%,顯效18例，有效8例，取得總有效率為100.00%。經(jīng)兩組比較，均無無效病例，總有效率無顯著性差異（P>0.05）,但臨床痊愈率比較差異明顯（△PV0.05）。結(jié)論補復方抗感顆粒的制備工藝簡便，質(zhì)量易于控制，對風熱型感冒治療的藥理作用明確，可安全應用于臨床，取得顯著
3、的臨床療效。關鍵詞：風熱型感冒；復方抗感顆粒；制備工藝/質(zhì)量控制Abstract:Objectivetostudythepreparationtechnologyofcompoundantisensegranules,typewindhotcoldtheclinicalapplicationofdiagnosisandtreatment?Methodsbyusingtheadvancedproductionprocessequipment,preparationofcompoundantisenseofgrains,technologicalprocessandqualitycontrol
4、arestudied,atthesametime,choosetobetween2011.03~2012.03coldpatients150casesofourhospital,outpatientdepartmentofourhospita1.Accordingtotheprincipleofrandomgroupingperiod,belongtogranulesandthetraditionalonegroup75caseseach.Traditionaloneandgranulesaremadeandthebatchnumber,andtheoriginofmedicinalmat
5、erialsmarket,accordingtotheirrespectiveprocessingrespectively.Traditionaloneaccordingtotheprescriptioncompatibilityoftheoriginaldoseaccordingtotake,andproceduresareroutinelytisanespan-fried,oral2timesaday.Granulestaketraditionalonedaycrudedrugs,preparationaccordingtoitsprocessinginto2bagofmedicine
6、,10gramsforeachbag.Abageachtime,2timesaday.Takingonlyfinishedwhenboilingwatertosoakfor3?5min,stiralittlecanbetaken.Resultsaftertreatmentwiththeabovemethod,granulegroupofpatientsrecoveredin67cases,cureratewas89.33%,6caseshadmarkedeffect,2caseseffectively,thetotaleffectiveratewas100.00%；Onegroupofpa
7、tientsrecoveredin49cases,curerateis65.33%,18caseshadmarkedeffect,8caseseffectively,thetotaleffectiveratewas100.00%?Comparisonoftwogroups,noinvalidcases,totaleffectiveratewasnosignificantdifference(P>0.05),butobvi
