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1、分類號學(xué)號D200978314學(xué)校代碼10487密級碩士學(xué)位論文碩士學(xué)位論文碩士學(xué)位論文碩士學(xué)位論文EXT2基因單核苷酸多態(tài)性與2型糖尿病易感性的薈萃分析學(xué)位申請人：楊徐學(xué)科專業(yè)：內(nèi)科學(xué)指導(dǎo)教師：汪道文教授答辯日期：2012年4月ADissertationSubmittedtoHuazhongUniversityofScienceandTechnologyfortheDegreeofMasterofMedicineTheassociationbetweenSNPsinEXT2andtype2diabetes:Ameta-a
2、nalysisCandidate:YangXuMajor:InternalMedicineSupervisor:Prof.DaoWenWangDivisionofCardiology,DepartmentofInternalMedicineTongjiHospital,TongjiMedicalCollegeHuazhongUniversityofScience&TechnologyWuhan430030,P.R.ChinaApril,2012獨(dú)創(chuàng)性聲明本人聲明所呈交的學(xué)位論文是我個人在導(dǎo)師指導(dǎo)下進(jìn)行的研究工作及取得的研究
3、成果。盡我所知，除文中已經(jīng)標(biāo)明引用的內(nèi)容外，本論文不包含任何其他個人或集體已經(jīng)發(fā)表或撰寫過的研究成果。對本文的研究做出貢獻(xiàn)的個人和集體，均已在文中以明確方式標(biāo)明。本人完全意識到本聲明的法律結(jié)果由本人承擔(dān)。學(xué)位論文作者簽名：日期：年月日學(xué)位論文版權(quán)使用授權(quán)書本學(xué)位論文作者完全了解學(xué)校有關(guān)保留、使用學(xué)位論文的規(guī)定，即：學(xué)校有權(quán)保留并向國家有關(guān)部門或機(jī)構(gòu)送交論文的復(fù)印件和電子版，允許論文被查閱和借閱。本人授權(quán)華中科技大學(xué)可以將本學(xué)位論文的全部或部分內(nèi)容編入有關(guān)數(shù)據(jù)庫進(jìn)行檢索，可以采用影印、縮印或掃描等復(fù)制手段保存和匯編本學(xué)位論文
4、。保密□，在年解密后適用本授權(quán)書。本論文屬于不保密□。（請在以上方框內(nèi)打“√”）學(xué)位論文作者簽名：指導(dǎo)教師簽名：日期：年月日日期：年月日目錄英文縮略詞·······································································1中文摘要··········································································2英文摘要··································
5、········································3正文············································································4研究背景······································································4材料與方法································································
6、···7結(jié)果······································································9討論····································································18參考文獻(xiàn)····································································20綜述·······································
7、···································25參考文獻(xiàn)····································································34致謝·········································································42華中科技大學(xué)碩士學(xué)位論文英文縮略詞表英文縮寫英文名稱中文名稱SNPSinglenucleotidepolymorphism單核苷酸多態(tài)性T2DMType
8、2diabetesmellitus2型糖尿病WHOWorldhealthorganization世界衛(wèi)生組織OROddsRatio比值比95%CI95%confidenceinterval95%置信區(qū)間MAFMinorallelefrequency次要等位基因頻率GWASGenome-wideassoc
