homer1a在小鼠腦缺血再灌注損傷中的作用及機制研究

homer1a在小鼠腦缺血再灌注損傷中的作用及機制研究

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時間:2019-03-15

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1、分類號R743.31第四軍醫(yī)大學UDC616.8TheFourthMilitaryMedicalUniversity密級公開碩士學位論文Homer1a在小鼠腦缺血再灌注損傷中的作用及機制研究馮樂霄培養(yǎng)類別全日制學位類型專業(yè)學位一級學科(專業(yè)類)臨床醫(yī)學二級學科(專業(yè))外科學(神外)研究方向缺血性腦損傷指導教師費舟教授(主任醫(yī)師)培養(yǎng)單位西京醫(yī)院神經外科二O一五年五月第四軍醫(yī)大學碩士學位論文目錄縮略語表·······································································

2、························1中文摘要·······························································································3ABSTRACT····························································································6前言·············································

3、·················································10文獻回顧······························································································12正文······························································································24實驗一Homer1a基因敲除小鼠的繁殖培育與基因

4、鑒定·································241材料·····························································································242實驗方法·······················································································253結果·········································

5、····················································284討論·····························································································29實驗二Homer1a在小鼠局灶性缺血再灌注腦損傷中的保護作用及對星形膠質細胞活化影響···············································································

6、·············31一小鼠局灶性腦缺血再灌注損傷模型建立·············································311材料··························································································312實驗方法···················································································323結果·····

7、·····················································································344討論··························································································36二Homer1a在腦缺血再灌注損傷中的保護作用及對星形膠質細胞活化影響···371材料················································

8、··········································382實驗方法········································

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