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1、分類號(hào)UDC密級(jí)公開miR-155在創(chuàng)面愈合中的作用及機(jī)制研究楊龍龍培養(yǎng)類別全日制學(xué)位類型學(xué)術(shù)學(xué)位一級(jí)學(xué)科(專業(yè)類)臨床醫(yī)學(xué)二級(jí)學(xué)科(專業(yè))外科學(xué)(燒傷)研究方向創(chuàng)面愈合指導(dǎo)教師胡大海教授(主任醫(yī)師)培養(yǎng)單位西京醫(yī)院燒傷與皮膚外科二O一五年五月第四軍醫(yī)大學(xué)博士學(xué)位論文目錄縮略語表·················································································································1中文摘要····················
2、·····························································································3ABSTRACT············································································································6前言·································································
3、··············································10文獻(xiàn)回顧···············································································································12正文···············································································································
4、27第一部分miR-155促進(jìn)創(chuàng)面愈合及相關(guān)機(jī)制研究··············································27實(shí)驗(yàn)一miR-155通過增快角質(zhì)形成細(xì)胞遷移加速創(chuàng)面上皮化而促進(jìn)創(chuàng)面愈合···281材料············································································································282方法···············································
5、·····························································303結(jié)果············································································································354討論···································································································
6、·········43實(shí)驗(yàn)二miR-155促進(jìn)角質(zhì)形成細(xì)胞遷移的機(jī)制研究··········································461材料············································································································462方法··················································································
7、··························483結(jié)果············································································································524討論············································································································58實(shí)驗(yàn)三miR-155對(duì)創(chuàng)面局部炎癥反應(yīng)及愈后纖維
8、化的影響·······························611材料··············