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《Antibiotic prophylaxis in prosthesis-based mammoplasty. A systematic review》由會員上傳分享，免費在線閱讀，更多相關(guān)內(nèi)容在學術(shù)論文-天天文庫。
1、InternationalJournalofSurgery15(2015)31e37ContentslistsavailableatScienceDirectInternationalJournalofSurgeryjournalhomepage:www.journal-surgery.netOriginalresearchAntibioticprophylaxisinprosthesis-basedmammoplasty:Asystematicreviewaaba,*NaisiHuang,MengyingLiu,PeirongYu,JiongWua
2、DepartmentofBreastSurgery,ShanghaiCancerCenter,FudanUniversity,No.270,DonganRd.,Shanghai200032,ChinabDepartmentofPlasticSurgery,MDAndersonCancerCenter,UniversityofTexas,Houston,TX77030,UnitedStateshighlightsExtendedsystemicantibioticprophylaxiswoulddecreaseinfectionriskinbreas
3、timplantsurgery.Topicalantibioticirrigationwoulddecreasecapsularcontracturerisk.Cephalosporinwasthemostcommonlypreferredantibioticregimen.Riskfactorsshouldbetakenintoconsiderationwhenprescribingantibioticprophylaxis.articleinfoabstractArticlehistory:Introduction:Althoughcons
4、ideredasanasepticsurgery,infectionafterprosthesis-basedmammoplastyReceived27October2014representstheleadingcauseofmorbidityafterreconstructiveandaestheticsurgery.Antibioticpro-Receivedinrevisedformphylaxisissupportedbyseveralstudiestopreventsurgicalsiteinfection(SSI)andcapsular
5、contracture23December2014(CC).However,thereisnohighqualityevidenceonantibioticprophylaxisinthisarea.Accepted24January2015Methods:AcomprehensiveliteraturesearchofMedline,EmbaseandCENTRALdatabaseswasconductedAvailableonline29January2015forstudiespublishedthroughJune2014.Studiesof
6、prosthesis-basedbreastsurgerywithcontrolgroupandantibioticprophylaxiswereincluded.Datawasanalyzedbymeta-analysisorsummarizedifnotKeywords:quali?edformeta-analysis.AntibioticsBreastResults:Atotalof13studieswereincluded.Basedonrandomeffectmodel,extendedsystemicantibioticImplantpr
7、ophylaxismorethan24hpostoperativelycouldsigni?cantlydecreaseinfectionrisk(pooledInfectionRR?0.638,95%CI0.453e0.898)comparedwithantibioticprophylaxiswithin24h.Insubgroupanalysis,Capsularcontractureextendedantibioticprophylaxiscouldsigni?cantlydecreaseSSIriskinimplantreconstructi
8、onsurgery(pooledRR?0.508,95%CI0.349e0.739),butnotinaes
