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1、萬方數(shù)據(jù)生堡匡堂盤查2Q!壘堡§旦絲旦箍塹鲞筮!!翅盟叢叢鯉』£!i塑:叢盟!!:!Q!!。!些!§:盟壘12白塞病心血管受累患者的臨床特點高娜韓薇慈維蘋廖華杜娟【摘要】目的分析總結(jié)白塞病心血管系統(tǒng)受累患者的臨床特點。方法回顧分析2002年1月至2014年1月在北京安貞醫(yī)院住院治療的35例白塞病心血管系統(tǒng)受累患者的臨床資料。35例中男27例,占77.1%;年齡:男(37±10)歲,女(36±9)歲。治療措施包括激素、免疫抑制劑、對癥治療、介入及外科手術(shù)。結(jié)果白塞病的心血管表現(xiàn)包括瓣膜病變(20例,57.1%)、傳導(dǎo)異常(10例,28.6%)、心內(nèi)血栓(
2、1例,2.9%)、動脈瘤(13例,37.1%)、動脈狹窄或閉塞(5例,14.3%)、肺動脈病變(3例,8.6%)、靜脈阻塞(4例,11.4%);同時存在1種以上的病變患者20例。炎癥指標(biāo)在各亞組間差異無統(tǒng)計學(xué)意義(P>0.05)。住院期間死亡2例。結(jié)論心血管系統(tǒng)損害是白塞病的嚴重臟器受累表現(xiàn),值得重視。多科協(xié)作有利于該疾病的診治?!娟P(guān)鍵詞】白塞?。恍难苁芾跜linicaldataanalysisofcardiovascularinvolvementinBehcet7SdiseaseG∞Na+.ttanWei.CiWeiping,LiaoHua,現(xiàn)Ju
3、an.‘AnzhenHospital,CapitalMedicalUniversity,&咖皤JDOD29,ChinaCorrespondingauthor:CaoNa,Email:gaoual230@J6acon【Abstract】0bjectiveToanalysistheclinicalfeaturesofcardiovascularinvolvementinBehcet’Sdisease.MethodsWereviewed35medicalrecordsofBehcet’SdiseasewithcardiovascularlesionsinAn
4、zhenHospital,CapitalMedicalUniversityfromJanuary2002toJanuary2014.77.1%patients(27/35)weremale.Themean(元土s)agewhencardiovasculardiseasesoccurwas37.19±10.4yearsinmaleand36.0土8.6yearsinfemalerespectively.ResultsTheclinicalspectrumofcardiovascularabnormalitiesincludedvalvularregurg
5、itation(20,57.1%),conductionsystemdisturbances(10,28.6%),intraeardiacthrombosis(1,2.9%),aneurysmsofthearteries(13,37.1%),arterystenosisorocclusion(5,14.3%),pulmonaryvasculardiseases(3,8.6%),venousthrombosis(4.11.4%).Twentypatientshadmorethanoneoftheselesions.Inflammatoryindicato
6、rshadnosignificantlydifferencebetweentheabovesubgroupsfP>0.05).Treatmentsincludedcorticosteroidsandimmunosuppressivedrugs.togetherwithsymptomatictreatments,interventiontherapyandoperation.Twoinpatientdiedfrommultipleorgandysfunctionsyndromeandcardiacshockrespectively.Conclusions
7、CardiovaseularinvolvementiSaremarkablesystemiclesionofBehcet’Sdisease.Multi—subjectcooperationiSbeneficialforthediagnosisandtreatmentofthedisease.【Keywords】Behcet7Sdisease;Cardiovascularinvolvement白塞病是一種可以累及大、中及小血管的非特異系統(tǒng)性血管炎。臨床主要特征為復(fù)發(fā)性口腔潰瘍、外陰潰瘍、眼葡萄膜炎,故又稱為口一眼一生殖器三聯(lián)征。重要臟器受累是白塞病預(yù)后不
8、良的重要原因。其中心血管系統(tǒng)受累病例約占總數(shù)的7%。40%,病死率高達29%¨剖。本研究回顧分