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1、咪瞠安定聯(lián)合異丙酚在電子胃腸鏡檢查術(shù)中臨床應(yīng)用[摘要]目的:研究靜脈麻醉咪哩安定和異丙酚聯(lián)合應(yīng)用于內(nèi)鏡檢查中的可行性和安全性。方法:應(yīng)用靜脈麻醉胃腸鏡檢查226例作為觀察組,常規(guī)胃腸鏡檢查238例作為對照組。胃腸鏡檢查均比較兩組檢查過程中的反應(yīng)、操作時間及檢查前后的心率、血壓、血氧飽和度變化。結(jié)果:觀察組所有患者無不適,愿意復(fù)檢者217例(96%);而對照組胃鏡167例(93%)患者難受、腸鏡58例(100%)患者難受,愿意復(fù)檢者78例(33%)o觀察組5?10min內(nèi)均完全清醒,均未遺留痛苦回憶。腸鏡組鎮(zhèn)靜麻醉成功率觀察組達回盲部48例(1
2、00%),對照組48例(83%)O觀察組檢查時間5?10min完成,而對照組為8^30min,兩組比較,差異有統(tǒng)計學(xué)意義。兩組均無嚴重不良反應(yīng)。結(jié)論:無痛性內(nèi)鏡檢查簡便易行安全,麻醉狀態(tài)下胃腸鏡檢查術(shù)可消除患者的緊張、恐懼情緒,操作順利,效果滿意,值得推廣應(yīng)用。[關(guān)鍵詞]靜脈麻醉;咪吐安定;異丙酚;胃鏡;腸鏡[中圖分類號]R614.2+4[文獻標識碼]C[文章編號]1674-4721(2011)08(b)-085-03Theclinicalapplicationofmidazolampluspropofolforgastrointestina
3、lendoscopyLIShuguangl,ZHANGLong2,RUANGuoyongl,LIANGAixial,QIUGuimeil1.DepartmentofInternalMedicine,thePeople,sHospitalofXinxingCounty,GuangdongProvince,Xinxing527400,China;2.DepartmemtofDigestion,theFirstPeople,sHospitalofGuangzhouCity,GuangdongProvince,Guangzhou510180,Chin
4、a[Abstract]Objective:Toinvestigatetheefficacyandsafetyofmidazolampluspropofolforgastrointestinalendoscopy.Methods:The226patientsasobservationgroupwerereceivedintravenousanesthesiagastrointestinalendoscopy,and238patientsascontrolgroupwerereceivedconventionalgastrointestinale
5、ndoscopy.consciousnessresponse,manipulationtime,cardiacrate,bloodpressure(BP),oxygensaturationofbloodoftheteogroupswereobserveredduringthestudy.ResuIts:Patientsinobservationgroupwereallwell,wantedtorechecking217cases(96%);Incontrolgroup,167(93%)patientsunwellinenteroscopean
6、d58(100%)patientsunwellingastroscope?Patientsinobservationgroupwereallcoldsoberin5~10minutes.48cases(100%)ofenteroscopereachedtoileocecusinobservationgroupand48cases(83%)incontrolgroup?Thereviewtimeofobservationgroupwas5-10minutesandcontrolgroupwas8~30minutes,therewasdiffer
7、encebetweenthetwogroups.Conclusion:Intravenousanesthesiaduringgastrointestinalendoscopycaneliminatepa/tients,fearmoodandimprovetheendoscopy.[Keywords]Intravenousanesthesia;Midazolam;Propofol;Gastroscope;Enteroscope胃腸鏡診療是目前診治消化道疾病最常用的主要方法,但有些患者對常規(guī)的胃腸鏡檢查產(chǎn)生一定的恐懼心理而拒絕檢查,以至延誤疾病的
8、診斷和治療。無痛苦胃腸鏡檢查是在常規(guī)胃腸鏡檢查和治療中應(yīng)用一定劑量的鎮(zhèn)痛及靜脈麻醉劑,使患者在清醒鎮(zhèn)靜或淺睡眠狀態(tài)下完成檢查和(或)治療,整個過程患者安全、舒適、無