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《妊娠合并甲狀腺功能減退和亞臨床甲狀腺功能減退與新生兒甲減的關(guān)系_張鑫越》由會(huì)員上傳分享,免費(fèi)在線閱讀,更多相關(guān)內(nèi)容在行業(yè)資料-天天文庫。
1、·90·中國優(yōu)生與遺傳雜志2016年第24卷第1期妊娠合并甲狀腺功能減退和亞臨床甲狀腺功能減退與新生兒甲減的關(guān)系張鑫越(河南宏力醫(yī)院婦產(chǎn)科,河南 長垣 453400)摘 要:目的 探討妊娠合并甲狀腺功能退減和亞臨床甲狀腺功能減退與新生兒甲減患病率的影響。方法 回顧性分析2007年1月—2014年1月在我院住院的妊娠合并甲狀腺功能減退69例,妊娠合并亞臨床甲狀腺功能減退123例,分析藥物治療妊娠合并甲減和亞臨床甲減以及孕期甲功達(dá)標(biāo)與否對(duì)新生兒甲狀腺功能減退患病率的影響。結(jié)果 藥物治療組新生兒甲減的患病率較非藥物組新生兒甲減患病率明顯下降(P<0.05)。藥物治療
2、亞臨床甲減與臨床甲減的孕婦其新生兒患病率無差別(P>0.05)。孕期TSH達(dá)標(biāo)的孕婦其新生兒患病率減少(P<0.05)。結(jié)論 對(duì)于妊娠合并甲狀腺功能減退或亞臨床甲狀腺功能減退的患者,均需要藥物的治療,并且在整個(gè)孕期中,我們盡可能使TSH達(dá)標(biāo),這樣就能減少或消除新生兒甲狀腺功能減退癥的患病率,從而達(dá)到優(yōu)生優(yōu)育的效果。關(guān)鍵詞:妊娠;甲狀腺功能減退;新生兒中圖分類號(hào):R722.1文獻(xiàn)標(biāo)識(shí)碼:B文章編號(hào):1006-9534(2016)01-0090-03DOI:10.13404/j.cnki.cjbhh.2016.01.037Combinedwithhypothyro
3、idismandsubclinicalthyroidfunctioninpregnancyandneonatalhypothyroidism.ZHANGXin-yue.(Dept.ofObstitric&Gynicol,HenanHongliHospital,HenanChangyuan453400)Abstract:Objective:Tostudythethyroidfunctioninpregnancywithdiminishedandsubclinicalhypothyroidismandneonatalhypothyroidismprevalence
4、rate.Methods:retrospectiveanalysisofJanuary2007toJanuary2014inourhospital69casesofpregnancycomplicatedhypothyroidism,subclinicalhypothyroidismduringpregnancyin123cases,analysisofdrugtherapycombinedwithhypothyroidismandsubclinicalhypothyroidismandthyroidfunctionduringpregnancy,standa
5、rdornotonneonatalhypothyroidismprevalencerateofpregnancy.Results:thetreatmentgroupofneonatalhypothyroidismprevalencethanwithouttreatmentofgroupneonatalhypothyroidismprevalenceratesignificantlydecreased(P<0.05).Drugtreatmentofsubclinicalhypothyroidismandsubclinicalhypothyroidismpregn
6、antwomen,hernewbornprevalencerateisnotdifference(P>0.05).pregnantwomenMonitoreTSHlevelduringpregnancyandletituptothestandard,hernewbornprevalenceratedecreased(P<0.05).Conclusion:forthepatientswithpregnancycomplicatedhypothyroidismorsubclinicalhypothyroidism,requiredrugtherapy,andthr
7、oughoutpregnancy,weasfaraspossibletomaketheTSHuptostandard,soitcanreduceoreliminatethemorbidityrateofneonatalhypothyroidismpatients,soastoachievetheeffectofprenatalandpostnatalcare.Keywords:Pregnancy;Hypothyroidism;Neonates原發(fā)性甲狀腺功能減退癥(簡稱:甲減22~38歲平均(30.1±5.3)歲(P>0.05)年齡無統(tǒng)計(jì)學(xué)差hypothyro
8、idism)是由于各種原因?qū)е禄颊叩图?/p>