資源描述:
《冠狀動(dòng)脈鈣化積分在冠心病診斷中的價(jià)值》由會(huì)員上傳分享,免費(fèi)在線閱讀,更多相關(guān)內(nèi)容在行業(yè)資料-天天文庫(kù)。
1、江蘇醫(yī)藥2015年4月第41卷第7期JiangsuMedJ,April2015,Vol41,No.7·773··論著·冠狀動(dòng)脈鈣化積分在冠心病診斷中的價(jià)值陶俊利王躍濤王建峰邵曉梁陸培奇【摘要】目的探討冠狀動(dòng)脈(冠脈)鈣化積分(CACS)在冠心?。ǎ茫粒模┰\斷中的價(jià)值。方法70例疑診CAD患者均行CACS和冠脈造影(ICA)檢查,用受試者工作特征(ROC)曲線評(píng)價(jià)CACS診斷CAD的效能,計(jì)算冠脈四大分支血管的CACS,分析分支血管CACS與相應(yīng)分支血管狹窄的相關(guān)性。結(jié)果ICA金標(biāo)準(zhǔn)診斷CAD47例,非CAD23例。CAD組CACS高于非CAD組[(586.6±1
2、20.0)分vs.(69.7±67.1)分](P<0.01)。CAD組四大分支血管的CACS均高于非CAD組(P<0.01)。CACS診斷CAD的ROC曲線下面積為0.873,診斷CAD最佳界值為122分,靈敏度、特異度、準(zhǔn)確度、陽(yáng)性預(yù)測(cè)值和陰性預(yù)測(cè)值分別為70.2%、95.7%、78.6%、97.1%和38.9%。分支血管CACS與相應(yīng)分支血管狹窄呈正相關(guān)(r=0.59,P<0.01)。結(jié)論CACS診斷CAD有一定價(jià)值,但不能全面評(píng)估冠脈狹窄程度?!娟P(guān)鍵詞】冠狀動(dòng)脈鈣化積分;冠心病【中圖分類號(hào)】R445【文獻(xiàn)標(biāo)識(shí)碼】A【文章編號(hào)】0253-3685(2015)
3、07-0773-03ValueofcoronaryarterycalciumscoreinthediagnosisofcoronaryarterydiseaseTAOJunli,WANGYuetao,WANGJianfeng,etal.DepartmentofNuclearMedicine,AffiliatedThirdHospital,SoochowUniversity,Changzhou213003,CHINA【Abstract】ObjectiveToevaluatethevalueofcoronaryarterycalciumscore(CACS)inth
4、ediagnosisofcoronaryarterydisease(CAD).MethodsSeventypatientswithsuspectedCADwereexaminedwithCACSandinvasivecoronaryangiography(ICA).CACSoffourmajorbranchvesselsofcoronaryarterywascalculated.TheperformanceofCACSinthediagnosisofCADwasevaluatedbydrawingreceiveroperationcurve(ROC).Theco
5、rrelationbetweenCACSofbranchvesselsandstenosisofcorrespondingvesselswasanalyzed.ResultsWithICAasgoldenstandard,CADwasdiagnosedin47cases(groupCAD)andnon-CADwasconfirmedin23cases(goupnon-CAD).CACSwashigheringroupCADthanthatingroupnon-CAD[(586.6±120.0)pointsvs.(69.7±67.1)points](P<0.01)
6、.SodidtheCACSoffourmajorbranchvesselsofcoronaryarteryingroupCAD(P<0.01).TheareaunderROCcurveforCACStodiagnoseCADwas0.873.Taking112pointsasthebestcutoffvalue,thesensitivitywas70.2%,specificitywas95.7%,accuracywas78.6%,positivepredictivevaluewas97.1%,andnegativepredictivevaluewas38.9%.
7、CACSofbranchvesselswaspositivelycorrelatedtothestenosisofcorrespondingvessels(r=0.59,P<0.01).ConclusionCACShasacertainvalueinthediagnosisofCAD,butcannotcomprehensivelyevaluatetheseverityofcoronarystenosis.【Keywords】Coronaryarterycalciumscore;Coronaryarterydisease[JiangsuMedJ,April201
8、5,41(7):773-