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1、咼尿酸血癥與急性脳梗死的關(guān)系臨床研究【摘要】目的:探討高尿酸血癥與急性腦梗死發(fā)生、發(fā)展的相關(guān)性。方法:選取2013年9月-2014年9月期間本院診治的120例急性腦梗死患者,根據(jù)空腹血清尿酸水平,將其分為高尿酸血癥組(急性腦梗死伴高尿酸血癥患者,40例)和正常尿酸組(血清尿酸水平止常的急性腦梗死患者,80例),根據(jù)1995年腦卒中臨床神經(jīng)功能缺損程度評(píng)分標(biāo)準(zhǔn),觀察和比較治療前兩組中重型、輕型神經(jīng)功能缺損程度比率、伴發(fā)疾病發(fā)生率以及治療后兩組臨床療效。結(jié)果:治療前高尿酸血癥組中重型神經(jīng)功能缺損發(fā)生率明顯高于正常尿酸組,輕型神經(jīng)功能缺損發(fā)生率低于正常尿酸組,兩組比較差異均有統(tǒng)計(jì)學(xué)意義(P〈0
2、.05);治療前高尿酸血癥組患者伴發(fā)疾?。ǚ逝?、高血壓、糖耐量異常、高脂血癥)的發(fā)生率高于正常尿酸組,高尿酸血癥組治療后的總有效率低于正常尿酸組,兩組比較差異均有統(tǒng)計(jì)學(xué)意義(卩〈0.05)。結(jié)論:高尿酸血癥與急性腦梗死患者的病情進(jìn)展呈相關(guān)性,是預(yù)后不良的重要預(yù)測因素。【關(guān)鍵詞】高尿酸血癥;急性腦梗死;相關(guān)性TheClinicalResearchoftheRelationshipbetweenHighUricAcidHematicDiseaseandAcuteCerebralinfarction/GUOJian-jun,NTXiao-jun,SHILi,etal.//MedicalInno
3、vationofChina,2015,12(26):051-053[Abstract]Objective:Todiscusstherelevanceofoccurrenceanddevelopmentwithhighuricacidhematicdiseaseandacutecerebralinfarction.Method:120patientswithacutecerebralinfarctioninourhospitalwereselectedfromSeptember2013toSeptember2014,accordingtothefastingserumuricacidlev
4、el,theyweredividedintohighuricacidhematicdiseasegroup(acutecerebralinfarctionpatientswithhighuricacidhematicdisease,40cases)andnormaluricacidgroup(acutecerebralinfarctionpatientswithnormalserumuricacidlevel,80cases),accordingtoa1995cerebralapoplexyclinicalnervefunctiondefectdegreegradingstandard,
5、thenervefunctiondefectratioofmoderateandseveredegreeandlightdegreebeforetreatment,concomitantdiseaseincidenceandclinicalcurativeeffectaftertreatmentoftwogroupswereobservedandcompared.Result:Beforetreatment,moderateandseveredegreenervefunctiondefectratioofhighuricacidhematicdiseasegroupwashigherth
6、annormaluricacidgroup,lightdegreenervefunctiondefect,ratioofhighuricacidhematicdiseasegroupwaslowerthannormaluricacidgroup,thedifferenceswerestatisticallysignificant(P〈0.05)?Beforetreatment,obesity,theincidenceofhighbloodpressure,abnormalglucosetoleranceandhyperlipidemiainhighuricacidhematicdisea
7、segroupwerehigherthannormaluricacidgroup,thedifferenceswerestatisticallysignificant(P<0.05)?Aftertreatment,thetotaleffectiveraleofhighuricacidhematicdiseasegroupwas1owerthannormaluricacidgroup,thedifferencewasstatistic