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1、20864r.qxd10/21/200511:23AMPage1062AssociationbetweeninfectionoftherespiratorytractattributabletobovinecoronavirusandhealthandgrowthperformanceofcattleinfeedlotsSarahL.Lathrop,DVM,PhD;ThomasE.Wittum,PhD;KennyV.Brock,DVM,PhD;StevenC.Loerch,PhD;LouisJ.Perino,
2、DVM,PhD;HowardR.Bingham,DVM,PhD;F.TedMcCollum,PhD;LindaJ.Saif,PhDinvestigators10isolatedBCVfrom38of100cattleObjective—Todeterminetheassociationbetweenrespiratorytractinfectionwithbovinecoronavirusinvolvedinoutbreaksofrespiratorytractdiseaseat(BCV),treatment
3、forrespiratorytractdisease,pul-feedlotsinKansasandArizona.Thatfindinghasmonarylesionsatslaughter,andaveragedailygaininpromptedconcernaboutthepossibleroleBCVmaycattleinfeedlots.playinthebovinerespiratorydiseasecomplexAnimals—837calvesinfeedlotsinOhioandTexas
4、.(BRDC)offeedlotcattle.Procedure—NasalswabspecimenswereobtainedConsideringtherolesofmultiplevirusesinBRDC,fromcattleatarrivalinafeedlot(day0)andatvariousitseemslikelythatBCV,withitstropismfortherespi-timesduringtheinitial28daysafterarrival.ratorytractandass
5、ociationwithpneumoniaincalves,SpecimensweretestedforBCV,usinganantigen-alsocouldcontributetothepathogenesisofBRDC.captureELISA.SerumsampleswereobtainedatAlthoughevidenceofBCVinfectionsinfeedlotcattleisarrivalandagain28daysafterarrivalandtestedforavailable,i
6、tisstilluncleartheroleitmayplayinantibodiestoBCV,usinganantibody-detectionELISA.BRDC,becausewefoundthatthevirusalsocouldbeInformationwascollectedregardingtreatmentforisolatedfromapparentlyhealthycattle.aTobettercattlewithrespiratorytractdiseaseandaveragedai
7、lydefinetheroleofBCVinBRDC,wesurveyed837gainduringthefeedingperiod.Pulmonarylesionsmixed-breedcattleentering4feedlotstodescribeshed-wereevaluatedatslaughter.dingpatternsofBCVfromtherespiratorytractandResults—CattlesheddingBCVfromthenasalcavityratesofexposur
8、e.Informationwascollectedontreat-anddevelopinganantibodyresponseagainstBCVmentratesforcattlewithrespiratorytractdisease,pul-were1.6timesmorelikelytorequiretreatmentformonarylesionsatslaughter,andaverag
