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1、VIROLOGICASINICA2016,31(1):1–2DOI:10.1007/s12250-016-3746-0EDITORIALCoronavirus:epidemiology,genomereplicationandtheinteractionswiththeirhostsZheng-LiShi1*,DeyinGuo2*,PeterJ.M.Rottier3*1.KeyLaboratoryofSpecialPathogens,WuhanInstituteofVirology,ChineseAcademyofScience
2、s,Wuhan430071,China2.StateKeyLaboratoryofVirology,CollegeofLifeSciences,WuhanUniversity,Wuhan430070,China3.VirologyDivision,DepartmentofInfectiousDiseasesandImmunology,FacultyofVeterinaryMedicine,UtrechtUniversity,Utrecht3584CL,NetherlandsThis?special?issue?of?the?jo
3、urnal?isthat?provides?new?insight?into?thepivotal?for?drug?screening?and?vac-dedicated?to?the?recent?progress?onepidemiology?of?coronaviruses?(Yipcine?development?against?the?dis-coronaviruses?and?covers?the?topicset?al.,?2016).?Niu?etal.?present?theeases?caused?by?c
4、oronaviruses.?Inof?viral?epidemiology,?virus?replica-development?of?a?new?two-tube?mul-this?issue,?Chen?and?Guo?give?antion?and?the?interactions?between?thetiplex?real-time?reverse?transcriptionoverview?of?recent?progresses?oncoronaviruses?and?their?hosts.PCR?to?dete
5、ct?six?human?coronavir-molecular?mechanisms?of?coronavir-Members?of?the?family?Coronavi-uses?(Niu?et?al.,?2016).?Three?art-us?RNA?capping?and?methylationridaeinfect?a?wide?range?of?verteb-icles,?authored?by?Ge?etal.,?Xu?etal.(Chen?et?al.,?2016).?Wang?etal.,rates?and?
6、humans.?They?usuallyand?Wang?etal.,?describe?differentsummarize?the?recent?advances?incause?respiratory,?gastrointestinal,discoveries?on?more?diverse?batbiological?and?structural?studies,?to-hepatic?and/or?central?nervous?sys-coronaviruses?including?SARS-likegether?w
7、ith?the?development?of?in-tem?diseases?of?humans,?livestockcoronaviruses,?highlighting?the?im-hibitors?targeting?coronavirus?pro-and?wild?animals.?Prior?to?the?out-portance?of?continued?further?re-teases?(Wang?et?al.,?2016).break?of?severe?acute?respiratory?sy-search
8、?on?bat-related?coronavirusesZoonotic?coronaviruses?are?be-ndrome?(SARS),?only?two?corona-(Ge?et?al.,?2016;?Wang?et?al.,?2016;comin