資源描述:
《順爾寧聯(lián)合喘可治佐治小兒毛細(xì)支氣管炎的臨床療效觀察.pdf》由會(huì)員上傳分享,免費(fèi)在線閱讀,更多相關(guān)內(nèi)容在應(yīng)用文檔-天天文庫。
1、·2686·現(xiàn)代生物醫(yī)學(xué)進(jìn)展w唧heI唧lyixue七0mProgressinModernBiomedicineVoL13NO.14MAY2013順爾寧聯(lián)合喘可治佐治d,JL毛細(xì)支氣管炎的臨床療效觀察林束珠白建文△平獻(xiàn)紅殷玉蘭。王春燕。(1上海同濟(jì)大學(xué)醫(yī)學(xué)院臨床三系上海200092;2上海同濟(jì)大學(xué)醫(yī)學(xué)院附屬東方醫(yī)院急診科上海200120;3上海交通大學(xué)醫(yī)學(xué)院附屬第九人民醫(yī)院分院奉城醫(yī)院上海201411)摘要目的:觀察順爾寧聯(lián)合喘可治佐治小兒毛細(xì)支氣管炎的臨床療效及其安全性。方法:選取2010年9月~2012年3月在我院兒科住院的70例毛細(xì)支氣管炎患兒作為觀察對(duì)象,按入
2、院先后順序隨機(jī)分為治療組和對(duì)照組,每組35例。兩組均常規(guī)給予抗感染、解痙平喘、吸氧、鎮(zhèn)靜等綜合治療,治療組在常規(guī)治療的基礎(chǔ)上加順爾寧(孟魯司特鈉咀嚼片)口服,每天4mg,每晚1次,以及喘可治注射液口服,每次半支,2次/日。治療7天后觀察和比較兩組患兒的臨床療效,并對(duì)所有病例門診隨訪3個(gè)月,觀察各組患兒在此期間喘息再次發(fā)作的情況。結(jié)果:治療7天后,治療組的總有效率為97.1%,對(duì)照組的有效率為80.0%,兩組間有顯著性差異(x7.83,P<0.05)。治療組癥狀體征平均持續(xù)時(shí)間均較對(duì)照組明顯縮短,差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。隨訪3個(gè)月內(nèi)治療組喘息反復(fù)發(fā)作的平均次數(shù)
3、顯著低于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。兩組均未見嚴(yán)重不良反應(yīng)。結(jié)論:順爾寧聯(lián)合喘可治佐治毛細(xì)支氣管炎臨床療效顯著,并能縮短住院時(shí)間,由于順爾寧可控制毛細(xì)支氣管炎后的氣道慢性炎癥,喘可治注射液可增強(qiáng)呼吸道抵抗能力、減少呼吸道反復(fù)感染,對(duì)毛細(xì)支氣管炎后喘息的反復(fù)發(fā)作有預(yù)防作用。關(guān)鍵闐:順爾寧;喘可治;毛細(xì)支氣管炎;臨床療效;喘息中圖分類號(hào):R725.6文獻(xiàn)標(biāo)識(shí)碼:A文章編號(hào):1673—6273(2013)14—2686—04ObservationOnmeClinicalEmcacyOfMontelukastplusChuankezhiinAdjunctiveT
4、reatmentofChildBronchiolitisL1NShu-zhu~,BAIJian—w鯽嬲.PINGXian-hong3,YINYu-lans,WANGChun-yan3(iThirdClinicalDepartment,ShanghaiTongjiUniversitySchoolofMedicine,ShanghaL200092,China;2DepartmentofEmergency,ShanghaiTongfiUniversityAfiliatedOdentalHospital,Shanghai,20012~China;3FengchengBranc
5、hHospitaloftheNinthPeople'sHospitalOfShanghai,afSliatedtoShanghaiJiaotongUniversity,Shanghai,201411,China)ABSTRACTObjective:Toexploretheclinicaleficacyandsafetyofmontelukastpluschuankezhiinadjunctivetreatmentofchildbronchiolitis.Methods:70casesofchildbronchiolitiswhoweretreatedinpediatr
6、icsdepartmentofourhospimlfromSeptember2010toMarch2012wererandomlydividedintotreatmentgroup(n=35)andcontrolgroup(n=35)accordingtotheorderofadmission.Allthepatientsweregivencomprehensivetreatmentincludingfightinfection,smoothingasthmaspasm,oxygen,calm,thetreatmentgroupwastreatedwithmontel
7、ukastorally,4mgperday,1timepernight,aswellaschuankezhiinjectionorally,halfeachtime,bid.Aftertreatmentfor7days,theclinicaleficacywasobservedandcompared,andallthecasesofoutpatientwerefollowed—upfor3months,therecurrenceofwheezewasobservedduringtheperiod.Results:Aftertreatmentfor7d