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1、154中華災害救援醫(yī)學2015年3月第3卷第3期ChineseJournalofDisasterMedicine,Vo1.3,No.3,March,2015硫酸鎂聯(lián)合丹參注射液治療妊娠中晚期羊水過少的臨床研究周傳亞,孫秀麗,文彩玲,楊海寧。【摘要】目的觀察硫酸鎂聯(lián)合丹參注射液等靜脈補液治療妊娠中晚期羊水過少的療效。方法將390例妊娠中晚期因羊水過少于筆者所在醫(yī)院住院治療的患者隨機分為3組:治療組和對照組A、對照組B,各130例。治療組采用硫酸鎂聯(lián)合丹參注射液等靜脈補液,對照組A采用復方丹參注射液等靜脈補液,對照組B則采用單純補液,治療周期皆為1個療程(7d),記錄治療后
2、三組的羊水指數(shù)、妊娠結(jié)局及新生兒情況,以判斷療效。結(jié)果治療組、對照組A與對照組B的治療總有效率分別為86.18%、54.46%及33.08%,三組總有效率有統(tǒng)計學差異(P<0.001),兩兩比較均有統(tǒng)計學差異(P<0.001)。三組妊娠結(jié)局不同(P<0.001),兩兩比較均不同(P=0.039,P<0.001,P<0.001)。三組新生兒窒息率無顯著性差異(P=0.361)。結(jié)論硫酸鎂聯(lián)合丹參注射液等靜脈補液治療妊娠中晚期羊水過少療效較好,值得推廣。【關(guān)鍵詞】羊水過少;硫酸鎂聯(lián)合丹參注射液;羊水指數(shù)【中國圖書分類號】R714Clinicalstudyonmagnesiu
3、msulfatecombinedwithsalviainjectioninthesecondandthirdtrimesterofpregnancywitholigo-hydramnios●●ZHOUChuanya,SUNXiuli,WENCailing,andYANGHaining.1.DepartmentofObstetricsandGynecology,PuyangMaternaland刪HealthCare,Puyang457000,China;2.DepartmentofMedicalAdministration,QinghaiProvincialCorpsH
4、ospital,ChinesePeople’sArmedPoliceForces,Xining810000,ChinaCorrespondingauthor:YANGHaining,E—mail:n.D6@163.corn【Abstract】ObjectiveToobserveeffectofmagnesiumsulfatecombinedwithsalviainjectioninthesecondandthirdtrimesterofpregnancywitholigohydramnios.MethodsAtotalof390casesofpatientsinthes
5、econdandthirdtrimesterofpregnancywitholi—gohydramnioswererandomlydividedinto3groups:treatmentgroup,controlgroupAandcontrolgroupB,130caseseach.Magnesiumsulfatecombinedwithsalviainjectionwasappliedtothetreatmentgroup,compositesalviainjectionwasusedinthecontrolgroupA,andmerefluidstransfusio
6、nwasgiventothecontrolgroupB.Allpatientsweretreatedfor1cycle(7d),andthenamnioticfluidin—dex,pregnancyoutcomeandincidenceofneonateasphyxiawererecordedandcompared.ResultsTotaleficiencyrateofthetreat—mentgroup,controlgroupAandc6ntrolgroupBwas86.18%,54.46%and33.08%respectively.Thedifferenceam
7、ongthethreegroupswasstatisticallysignificant(P<0.001),andthedifferencesbetweeneachtwogroupswerealsostatisticallysignificant(P<0.001).Pregnancyoutcomeamongthethreegroupswasstatisticallydifferent(P<0.001),andalsothedifferencesbetweeneachtwogroupswerestatisticallysignificant