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《丙戊酸鈉聯(lián)合平癇顆粒與卡馬西平聯(lián)合恩必普治療腦卒中后癲癇的臨床療效、對(duì)患者認(rèn)知功.》由會(huì)員上傳分享,免費(fèi)在線閱讀,更多相關(guān)內(nèi)容在應(yīng)用文檔-天天文庫。
1、丙戊酸鈉聯(lián)合平癇顆粒與卡馬西平聯(lián)合恩必普治療腦卒中后癲癇的臨床療效、對(duì)患者認(rèn)知功能的改善及安全性對(duì)比陳靜目的分析和探討丙戊酸鈉聯(lián)合平癇顆粒與卡馬西平聯(lián)合恩必普治療腦卒屮后癲癇(EAS)的臨床療效、對(duì)患者認(rèn)知功能的改善及安全性。方法選取我院2013年3月~2014年3月收治的82例腦卒屮后癲癇患者,通過隨機(jī)數(shù)字表法分為甲組(n=41)和乙組(n=41),甲組患者采用卡馬西平聯(lián)合恩必普治療,乙組患者采用丙戊酸鈉聯(lián)合平癇顆粒治療,對(duì)兩組患者臨床治療效果、認(rèn)知功能改善及不良反應(yīng)發(fā)生情況進(jìn)行分析。結(jié)果甲組患者治療有效率75.61
2、%,較乙組87.80%更低(P<0.05);甲組患者認(rèn)知功能改善明顯優(yōu)于乙組(P<0.05);兩組患者不良反應(yīng)發(fā)生率比較無明顯差異(P>;0.05)o結(jié)論針對(duì)腦卒屮沿癲癇患者,丙戊酸鈉聯(lián)合平癇顆粒與卡馬西平聯(lián)合恩必普均能實(shí)現(xiàn)不錯(cuò)的臨床效果,前者治療效果優(yōu)于后者,后者認(rèn)知功能改善優(yōu)于前后,兩種方法治療不良反應(yīng)少,安全性高,值得臨床推廣應(yīng)用。【關(guān)鍵詞】腦卒中后癲癇;丙戊酸鈉;平癇顆粒;卡馬西平;恩必普;認(rèn)知功能;臨床療效CombinedwithsodiumvalproatePingxiangranulesa
3、ndcarbamazepinecombinedgracewillbeuniversalinthetreatmentofpost-strokeepilepsy,cognitivefunctionofthepatientswithimprovementandsafetycompared【Abstract】ObjectivetoanalyzeanddiscusscombinedwithsodiumvalproatePingxiangranulesandcarbamazepinecombinedgracewillbeunive
4、rsalinthetreatmentofpost-strokeepilepsy(EAS)theclinicalcurativeeffect,oncognitivefunctioninpatientswithimprovementandsafety.MethodsselectedinourhospitalinMarch20132014Marchwere82casesofcerebralstrokeinpatientswithepilepsyafter,accordingtotherandomnumbertablemeth
5、odweredividedintogroupA(n=41)andgroupB(n=41),Division1patientswithcarbamazepinecombinedgracewillgeneraltreatment,groupBpatientsusingcombinedwithsodiumvalproatePingxiangranulestreatment,oftwogroupsofpatientswithclinicalcurativeeffect,improvecognitivefunctionandad
6、versereactionincidencewereanalyzed.ResultsgroupApatientswas75.6%,comparedwiththegroupB87.80%lower(P<0.05);cognitivefunctioninpatientswithfirstdivisionimprovewassignificantlybetterthanthatofgroupB(P<0.05).Theadversereactionsofthetwogroupsofpatientsoccurredr
7、atehadnosignificantdifference(P>0.05).Conclusionforpatientswithepilepsyafterstroke,combinedwithsodiumvalproatePingxiangranulesandcarbamazepinecombinedGrace&Pmustcanachievegoodclinicaleffects,thetreatmenteffectoftheformerisbetterthanthelatterandthecognitiv
8、efunctionimprovedthanbeforeandafter,twokindsoftreatmentwithlessadversereaction,highsecurity,itisworthofclinicalapplication.【Keywords】ofpost-strokeepilepsy;sodiumvalpr