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1、妊娠皮膚病簡(jiǎn)介生理的變化Enlargedoftheintermediatelobeofthepituitarygland,themelanocyte-stimulatinghormone(MSH)becameremarkablyelevatedby8weeksgestation常見的變化-Hyperpigmentation90%:skindarkening;MSHandestrogenBeginningearlyinpregnancyandmorepronouncedinnaturallyhyperpig
2、mentedareassuchasareolare,perineumandumbilicusandaxillaeandinnerthigns,LineanigraFace:cholasmaormelasma;50%,sunscreens;Regresspostpartum,dermalmelanosispersistupto10yearsin1/3pts2-5%hydroxquinone,0.1%tretinoingelorcreamor20%azelaicacidcreamcholasmaormelas
3、ma黑斑or肝斑Lineanigra常見的變化-NaviPigmentedcutaneoustumorscommonlyenlargeanddarkenduringpregnancy,leadingtotheirconfusionwithmalignantmelanomas.6%changedindiameteroverpregnancyNoevidencethattheyundergomalignanttransformations常見的變化-HairGrowthGrowinghairphaseisin
4、creasedrelatedtotherestinghairphaseEstrogenprolongthegrowinghairphaseandandrogenscauseenlargementoffolliclesTelogeneffluvium:abrupthairlossbeginning1to4monthspostpartum;selflimitedandrestoredin6to12months常見的變化-VascularchangeAugmentedcutaenousbloodflow:est
5、rogenanddecreasedvascularresistanceSpiderangiomas:2/3whiteand1/10blackPalmarerythema:2/3whiteand1/3blackPapillaryhemangiomas:5%Pregnancygingivitis(epulis):growthofthegumcapillariesPyogenicgranulomaofpregnancy(granulomagravidarum):oralcavityandarisefromthe
6、gingivalpapillaeSpiderangiomasPalmarerythemaPregnancygingivitis(epulis)Pyogenicgranulomaofpregnancy妊娠紋80～90﹪的孕婦懷孕6～7個(gè)月後開始產(chǎn)生，除了肚子之外，大腿、腹股溝甚至胸部都有可能出現(xiàn)粉紅或紫紅色萎縮性斑紋。除了荷爾蒙的影響，體重增加太快也是促成原因之一。雖然在產(chǎn)後會(huì)慢慢變白、變細(xì)，但很多人是無法完全恢復(fù)的控制體重含果酸的乳液或其他可促進(jìn)彈力纖維生成的妊娠霜，來緊緻皮膚，預(yù)防妊娠紋產(chǎn)生。倘若妊娠紋
7、已產(chǎn)生，在產(chǎn)後且妊娠紋尚未變白前，可接受脈衝光治療，有改善的機(jī)會(huì)。Dermatosesofpregnancy1.6%ofwomenhadsignificantpruritusatsometimeduringprengancyPruritusgravidarumPrurutucureticarialpapulesandplaquesofpregnancyHerpesgestationisPruritusGravidarum0.6%pregnancywithpruritus:mildvariantofintr
8、ahepaticcholestasisofpregnancyScratchingandexcoriation?skinlesionsHormone,geneticsandenviornmentalfactorsPruriticurticarialpapulesandplaquesofpregnancyPUPPPinUS;Polymorphiceruptionofpregnancy(PEP)inUK1/200singleton,
